In their recent investigation involving differential operators for the generalized Lagrange polynomials, Chan et. al. [3] encountered and proved a certain summation identity and several other results for the Lagrange polynomials in several variables, which are popularly known in the literature as the Chan-Chyan-Srivastava polynomials. These multivariable polynomials have been studied systematically and extensively in the literature ever since then (see, for example, [1], [4], [9], [11], [12] and [13]). In the present paper, we investigate umbral calculus presentations ofthe Chan-Chyan-Srivastava polynomials and also of their substantially more general form, the Erkus-Srivastava polynomials [9]. Some other closely-related results are also considered.