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dc.creatorCortés M,Claudia
dc.creatorOksenberg R,Danny
dc.creatorAfani S,Alejandro
dc.creatorDefilippi C,Carlos
dc.creatorMadrid S,Ana María
dc.date2004-11-01
dc.date.accessioned2019-04-25T13:14:23Z
dc.date.available2019-04-25T13:14:23Z
dc.identifierhttps://scielo.conicyt.cl/scielo.php?script=sci_arttext&pid=S0034-98872004001100008
dc.identifier.urihttp://revistaschilenas.uchile.cl/handle/2250/72048
dc.descriptionBackground: Esophageal candidiasis is associated with conditions that cause an immune depression. It is a defining disease for AIDS, is observed in poorly controlled diabetics, in patients with renal or hepatic failure, in patients with cancer and in subjects using medications causing immunosuppression or broad spectrum antimicrobials. Aim: To report the features of 10 immunocompetent patients with esophageal candidiasis. Patients and methods: Six males and four females aged between 48 and 82 years, without conditions associated with immunosuppression, in whom an esophageal candidiasis was found on an upper gastrointestinal endoscopy. Delayed skin hypersensitivity to eight antigens, Iymphocyte subpopulations, yeast phagocytosis and neutrophil chemotaxis were measured. Results: Six patients had a low CD4 Iymphocyte count and seven had a low CD8 count. Seven patients were anergic on skin hypersensitivity challenge. Yeast phagocytosis was abnormal in one patient and neutrophil chemotaxis was abnormal in two. Humoral immunity was normal in all subjects. All patients were treated with oral fluconazole in doses of 150 mg/day for 14 days, with complete resolution of candidiasis in all. Conclusions: Patients with esophageal candidiasis, have frequent alterations of cellular immunity, that must be diagnosed and treated
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dc.languagees
dc.publisherSociedad Médica de Santiago
dc.relation10.4067/S0034-98872004001100008
dc.rightsinfo:eu-repo/semantics/openAccess
dc.sourceRevista médica de Chile v.132 n.11 2004
dc.subjectCandidiasis
dc.subjectesophageal
dc.subjectImmunity
dc.subjectcellular
dc.subjectImmunocompetence
dc.titleCandidiasis esofágica en pacientes inmunocompetentes: Estudio clínico e inmunológico


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