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dc.contributoren-US
dc.creatorMacías-Villamizar, Víctor
dc.creatorCuca-Suárez, Luís
dc.date2017-06-16
dc.date.accessioned2019-09-10T17:53:35Z
dc.date.available2019-09-10T17:53:35Z
dc.identifierhttp://www.jcchems.com/index.php/JCCHEMS/article/view/179
dc.identifier.urihttps://revistaschilenas.uchile.cl/handle/2250/108676
dc.descriptionIn the genus Nectandra, the presence of certain types of secondary metabolites has been determined, including sesquiterpenes, phytosterols, polyalcohols, arylpropionic acid derivatives, flavonols, arylpropanoids, furofuran lignans, dihydrobenzofuran neolignans [1], and certain norlignans [2], alkaloids [3], tannins [4], diterpenes [5], and components of essential oils [6]. However, the chemotaxonomic characteristics are determined by the presence of lignan-type compounds [7]. The ultimate goal of structural modification of natural products is to obtain new drugs [8]. In that sense, there is a growing interest in lignans and their synthetic derivatives due to applications in cancer chemotherapy and various other pharmacological effects [9]. This work corresponds to the first report of this type of structural modification of lignan compounds (7,7’-epoxylignans and diaryldimethylbutane lignans) isolated from Nectandra species. Therefore, this work can be used as a starting point for structure-activity relationship studies.en-US
dc.formatapplication/pdf
dc.languageeng
dc.publisherSociedad Chilena de Químicaen-US
dc.relationhttp://www.jcchems.com/index.php/JCCHEMS/article/view/179/141
dc.rightsCopyright (c) 2017 Víctor Macías-Villamizar, Luís Cuca-Suárezen-US
dc.rightshttp://creativecommons.org/licenses/by-nc-sa/4.0en-US
dc.sourceJournal of the Chilean Chemical Society; Vol 62, No 2 (2017): Journal of the Chilean Chemical Societyen-US
dc.source0717-9707
dc.subjecten-US
dc.titleSTRUCTURAL MODIFICATION OF LIGNAN COMPOUNDS ISOLATED FROM NECTANDRA SPECIES (LAURACEAE)en-US
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.typeen-US


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