dc.contributor | | en-US |
dc.creator | Zayed, Sayed I. M. | |
dc.creator | Al-Talhi, Amal A. H. | |
dc.creator | Al Thagafi, Asmaa E. | |
dc.date | 2018-09-12 | |
dc.date.accessioned | 2019-09-10T17:53:36Z | |
dc.date.available | 2019-09-10T17:53:36Z | |
dc.identifier | http://www.jcchems.com/index.php/JCCHEMS/article/view/764 | |
dc.identifier.uri | https://revistaschilenas.uchile.cl/handle/2250/108693 | |
dc.description | The electrochemical oxidation of hydroxyzine dihydrochloride at carbon paste electrode has been studied in 0.04 M Britton-Robinson buffer pH 6.2 using cyclic and differential pulse voltammetry. The oxidation process has been shown to irreversible and diffusion controlled with adsorption characterstics. Based on these studies, simple, rapid, and sensitive differential pulse anodic voltammetric method has been developed for the determination of the drug over the concentration range 0.45-5.36 μg/ml, with detection and quantification limits of 0.27 and 0.90 μg/ml hydroxyzine dihydrochloride, respectively. The proposed method was successfully used for quantification of hydroxyzine dihydrochloride in Atarax tablets and spiked human urine. | en-US |
dc.format | application/pdf | |
dc.language | eng | |
dc.publisher | Sociedad Chilena de Química | en-US |
dc.relation | http://www.jcchems.com/index.php/JCCHEMS/article/view/764/255 | |
dc.rights | Copyright (c) 2018 Journal of the Chilean Chemical Society | en-US |
dc.rights | http://creativecommons.org/licenses/by-nc-sa/4.0 | en-US |
dc.source | Journal of the Chilean Chemical Society; Vol 63, No 3 (2018): Journal of the Chilean Chemical Society | en-US |
dc.source | 0717-9707 | |
dc.subject | Hydroxyzine dihydrochloride; differential pulse anoding voltammetry; carbon paste electrodes; pharmaceutical dosage form; human urine | en-US |
dc.title | DETERMINATION OF HYDROXYZINE BY DIFFERENTIAL PULSE ANODIC VOLTAMMETRY USING CARBON PASTE ELECTRODE | en-US |
dc.type | info:eu-repo/semantics/article | |
dc.type | info:eu-repo/semantics/publishedVersion | |
dc.type | | en-US |