ROLE OF SURGERY IN SAPROCHAETE CAPITATA (S. CAPITATA) SEPSIS IN A PATIENT WITH ACUTE MYELOID LEUKEMIA. CASE REPORT

Rol de la cirugía en el manejo de la infección invasora por Saprochaete capitata. Presentación de un caso y revisión de la literatura

Author
Radich R, Jasna; Universidad de Chile

Álvarez Z, Carlos; Universidad de Chile, Universidad de Santiago de Chile, Hospital Barros Luco Trudeau

Valenzuela R, Ana; Universidad de Chile

Castillo H, Felipe; Universidad de Chile, Hospital Barros Luco Trudeau

Moraga V, Francisco; Universidad de Chile

Castillo A, Jorge; Hospital Barros Luco

Full text
http://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/view/5611
Abstract
Saprochaete capitata (S. capitata) fungal sepsis is a severe condition with a clinical presentation that is similar to other yeast originated fungal sepsis. It is observed in patients with hematological malignancies such as acute myeloid leukemia and neutropenia. We report a 23 year old male presenting with cough, fever and malaise. A bone marrow biopsy led to the diagnosis of acute myeloid leukemia. During the first cycle of chemotherapy the patient presented fever: blood cultures were positive for Klebsiella pneumoniae. Despite antimicrobial treatment, fever persisted; a computed tomography showed a focal splenic lesion; a left exudative pleural effusion appeared. A Matrix Assisted Laser Desorption Ionization –Time of Flight mass spectrometry identified the presence of S capitata. After multiple antifungal treatments and pleural cavity cleansing by means of videothoracoscopy and laparoscopic splenectomy, the infection resolved and the patient completed his chemotherapy.
 
Saprochaete capitata (S. capitata) fungal sepsis is a severe condition with a clinical presentation that is similar to other yeast originated fungal sepsis. It is observed in patients with hematological malignancies such as acute myeloid leukemia and neutropenia. We report a 23 year old male presenting with cough, fever and malaise. A bone marrow biopsy led to the diagnosis of acute myeloid leukemia. During the first cycle of chemotherapy the patient presented fever: blood cultures were positive for Klebsiella pneumoniae. Despite antimicrobial treatment, fever persisted; a computed tomography showed a focal splenic lesion; a left exudative pleural effusion appeared. A Matrix Assisted Laser Desorption Ionization –Time of Flight mass spectrometry identified the presence of S capitata. After multiple antifungal treatments and pleural cavity cleansing by means of videothoracoscopy and laparoscopic splenectomy, the infection resolved and the patient completed his chemotherapy.
 
Metadata
Show full item record