| dc.contributor | NIH | es-ES |
| dc.creator | Durán-Aniotz, Claudia; University of Texas Health Science Center at Houston | |
| dc.creator | Moreno-González, Inés; University of Texas Health Science Center at Houston | |
| dc.creator | Morales, Rodrigo; University of Texas Health Science Center at Houston | |
| dc.date | 2013-04-05 | |
| dc.date.accessioned | 2019-11-11T18:26:22Z | |
| dc.date.available | 2019-11-11T18:26:22Z | |
| dc.identifier | http://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/view/1946 | |
| dc.identifier.uri | https://revistaschilenas.uchile.cl/handle/2250/110669 | |
| dc.description | AMYLOID AGGREGATES: ROLE IN PROTEIN MISFOLDING DISORDERS Misfolding and aggregation of proteins are the main features of a group of diseases termed Protein Misfolding Disorders (PMDs). PMDs include Alzheimer’s disease and Transmissible Spongiform Encephalopathies, among many others. The deposition of protein aggregates is the main responsible for tissue damage and the consequent clinical signs generated in such disorders. In this review, we will focus in the role of protein aggregates in these diseases and in the putative mechanisms by which they exert their toxicity. | es-ES |
| dc.format | application/pdf | |
| dc.language | spa | |
| dc.publisher | Revista Médica de Chile | es-ES |
| dc.relation | http://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/view/1946/125 | |
| dc.relation | http://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/downloadSuppFile/1946/4991 | |
| dc.relation | http://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/downloadSuppFile/1946/4992 | |
| dc.relation | http://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/downloadSuppFile/1946/4993 | |
| dc.relation | http://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/downloadSuppFile/1946/4994 | |
| dc.relation | http://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/downloadSuppFile/1946/6139 | |
| dc.relation | http://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/downloadSuppFile/1946/6509 | |
| dc.relation | http://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/downloadSuppFile/1946/6510 | |
| dc.relation | http://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/downloadSuppFile/1946/6511 | |
| dc.source | Revista Médica de Chile; Vol. 141, núm. 4 (2013): ABRIL 2013 | es-ES |
| dc.source | 0034-9887 | |
| dc.subject | Alzheimers disease; Amyloid; Prion diseases; Protein misfolding; Protestasis deficiencies | es-ES |
| dc.title | Agregados amiloides: rol en Desórdenes de Conformación Proteica | es-ES |
| dc.type | info:eu-repo/semantics/article | |
| dc.type | info:eu-repo/semantics/publishedVersion | |
| dc.type | | es-ES |
