PNEUMOMEDIASTINUM AND CUTANEOUS NECROSIS IN DERMATOMYOSITIS. REPORT OF ONE CASE
Neumomediastino y necrosis cutánea en asociación a dermatomiositis: presentación de un caso clínico y revisión de la literatura
Author
Gallardo C, Natalia
Valenzuela L, Omar; Clínica Alemana de Santiago
Hospital Padre Hurtado
Universidad del Desarrollo
Ibáñez V, Sebastián; Clínica Alemana de Santiago
Hospital Padre Hurtado
Universidad del Desarrollo
Abstract
We report a 37 years old diabetic male with a dermatomyositis treated with oral cyclophosphamide. He was admitted to the hospital due to a zone of skin necrosis with purulent exudate, located in the second left toe. A complete blood count showed a leukocyte count of 2600 cells/mm3. A Chest CAT scan showed a pneumomediastinum with emphysema of adjacent soft tissue. Cyclophosphamide was discontinued and leukocyte count improved. The affected toe was amputated and a chest CAT scan showed a partial resolution of the pneumomediastinum. We discuss and review the pathogenesis, clinical presentation and management of pneumomediastinum and cutaneous necrosis in association with dermatomyositis. We report a 37 years old diabetic male with a dermatomyositis treated with oral cyclophosphamide. He was admitted to the hospital due to a zone of skin necrosis with purulent exudate, located in the second left toe. A complete blood count showed a leukocyte count of 2600 cells/mm3. A Chest CAT scan showed a pneumomediastinum with emphysema of adjacent soft tissue. Cyclophosphamide was discontinued and leukocyte count improved. The affected toe was amputated and a chest CAT scan showed a partial resolution of the pneumomediastinum. We discuss and review the pathogenesis, clinical presentation and management of pneumomediastinum and cutaneous necrosis in association with dermatomyositis.