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Tormenta de citoquinas: reacción adversa inhabitual por rituximab. Caso Clínico

dc.contributoren-US
dc.contributores-ES
dc.creatorPalma, Estefanía
dc.creatorGonzalez, Vicente
dc.creatorGrünholz, Daniela
dc.creatorLandaeta, María
dc.creatorMallea, María
dc.creatorPérez, José
dc.creatorArmstrong, Tomás
dc.date2017-01-09
dc.date.accessioned2019-11-11T18:26:36Z
dc.date.available2019-11-11T18:26:36Z
dc.identifierhttp://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/view/4989
dc.identifier.urihttps://revistaschilenas.uchile.cl/handle/2250/110765
dc.descriptionRituximab is a plausible alternative first-line treatment of ANCA-associated vasculitis. Adverse effects related to its infusion are common and usually have a benign course. However, there have been reports of refractory cardiogenic shock simulating septic shock. We report an 81 years male with the diagnosis of ANCA associated vasculitis. Rituximab 500 mg was administered intravenously for a relapse. The infusion proceeded without incident. However, 24 hours after its administration the patient began with fever, chills, coughing and strong malaise. The patient was transferred to the critical patient unit where a septic shock was suspected and resuscitative measures were started. However, the fast response to moderate doses of vasoactive drugs and complementary tests did not support an infectious etiology for the shock. Antimicrobials were discontinued and systemic corticosteroids were maintained, achieving remission of the symptoms. Shock as an unusual adverse reaction to Rituximab was suspected.en-US
dc.descriptionRituximab is a plausible alternative first-line treatment of ANCA-associated vasculitis. Adverse effects related to its infusion are common and usually have a benign course. However, there have been reports of refractory cardiogenic shock simulating septic shock. We report an 81 years male with the diagnosis of ANCA associated vasculitis. Rituximab 500 mg was administered intravenously for a relapse. The infusion proceeded without incident. However, 24 hours after its administration the patient began with fever, chills, coughing and strong malaise. The patient was transferred to the critical patient unit where a septic shock was suspected and resuscitative measures were started. However, the fast response to moderate doses of vasoactive drugs and complementary tests did not support an infectious etiology for the shock. Antimicrobials were discontinued and systemic corticosteroids were maintained, achieving remission of the symptoms. Shock as an unusual adverse reaction to Rituximab was suspected.es-ES
dc.formatapplication/pdf
dc.languagespa
dc.publisherRevista Médica de Chilees-ES
dc.relationhttp://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/view/4989/2808
dc.relationhttp://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/downloadSuppFile/4989/23219
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dc.relationhttp://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/downloadSuppFile/4989/23562
dc.relationhttp://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/downloadSuppFile/4989/26377
dc.sourceRevista Médica de Chile; Vol. 145, núm. 2 (2017): FEBRERO 2017es-ES
dc.source0034-9887
dc.subjectAnti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Drug-Related Side Effects and Adverse Reactions; Rituximab; Shocken-US
dc.subjectAnti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Drug-Related Side Effects and Adverse Reactions; Rituximab; Shockes-ES
dc.titleSHOCK AS AN ADVERSE REACTION TO RITUXIMAB. CASE REPORTen-US
dc.titleTormenta de citoquinas: reacción adversa inhabitual por rituximab. Caso Clínicoes-ES
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.typees-ES


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