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ERYTHEMA NODOSUM. ANALYSIS OF 91 HOSPITALIZED PATIENTS

Eritema nodoso: Causas más prevalentes en pacientes que se hospitalizan para estudio, y recomendaciones para el diagnóstico.

dc.contributoren-US
dc.contributorEscuela de Medicina de la Pontificia Universidad Católica de Chilees-ES
dc.creatorVaras, Pablo; Escuela de Medicina Pontificia Universidad Católica de Chile
dc.creatorAntúnez-Lay, Andrea; Escuela de Medicina Pontificia Universidad Católica de Chile
dc.creatorBernucci, José Miguel; Escuela de Medicina Pontificia Universidad Católica de Chile
dc.creatorCossio, Laura; Escuela de Medicina Pontificia Universidad Católica de Chile
dc.creatorGonzález, Sergio; Escuela de Medicina Pontificia Universidad Católica de Chile
dc.creatorEymin, Gonzalo; Escuela de Medicina de la Pontificia Universidad Catolica de Chile
dc.date2016-01-15
dc.date.accessioned2019-11-11T18:26:43Z
dc.date.available2019-11-11T18:26:43Z
dc.identifierhttp://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/view/4307
dc.identifier.urihttps://revistaschilenas.uchile.cl/handle/2250/110792
dc.descriptionBackground: Erythema Nodosum (EN) is an acute nodular erythematous cutaneous eruption. It is presumed to be a hypersensitivity reaction and it may be idiopathic, or occur in association with diverse diseases and medications. Aim: To identify the main etiologies of EN among patients admitted to a medicine service of a clinical hospital. Material and Methods: Analysis of medical records of patients discharged with the diagnosis of EN during a ten years period. Patients were considered to have secondary EN when an underlying condition was found, and to have idiopathic EN when no such condition was found. Results: One hundred twenty nine patients were identified, but 91, aged 38 ± 14 years (86% females) had available clinical information. The etiology was idiopathic in 32 and secondary in 68% of patients. The leading etiologies were post-Streptococcal in 32%, followed by sarcoidosis in 11%, primary tuberculosis in 7%, Mycoplasma infection in 3%, Bartonella infection in 3%, Behçet’s syndrome in 2%, inflammatory bowel disease in 2%, drugs in 1% and other etiologies in 8%. Secondary cases of EN had higher levels of C Reactive Protein and leucocytes than idiopathic cases. Conclusions: The distribution of causes in our study population were similar to those reported in the literature (With smaller proportion of idiopathic), as was the man / woman (1/6) ratio, and the preponderance of cases in winter and spring. Infectious diseases were the leading causes of EN in this group of patients, and a reasonable initial approach in the hospital should include a diligent medical history and physical examination, complete blood count, VHS, titles ASO, PPD, chest X-ray or CT scan and, where deemed appropriate, specific autoimmune and infectious serology.en-US
dc.descriptionBackground: Erythema Nodosum (EN) is an acute nodular erythematous cutaneous eruption. It is presumed to be a hypersensitivity reaction and it may be idiopathic, or occur in association with diverse diseases and medications. Aim: To identify the main etiologies of EN among patients admitted to a medicine service of a clinical hospital. Material and Methods: Analysis of medical records of patients discharged with the diagnosis of EN during a ten years period. Patients were considered to have secondary EN when an underlying condition was found, and to have idiopathic EN when no such condition was found. Results: One hundred twenty nine patients were identified, but 91, aged 38 ± 14 years (86% females) had available clinical information. The etiology was idiopathic in 32 and secondary in 68% of patients. The leading etiologies were post-Streptococcal in 32%, followed by sarcoidosis in 11%, primary tuberculosis in 7%, Mycoplasma infection in 3%, Bartonella infection in 3%, Behçet’s syndrome in 2%, inflammatory bowel disease in 2%, drugs in 1% and other etiologies in 8%. Secondary cases of EN had higher levels of C Reactive Protein and leucocytes than idiopathic cases. Conclusions: The distribution of causes in our study population were similar to those reported in the literature (With smaller proportion of idiopathic), as was the man / woman (1/6) ratio, and the preponderance of cases in winter and spring. Infectious diseases were the leading causes of EN in this group of patients, and a reasonable initial approach in the hospital should include a diligent medical history and physical examination, complete blood count, VHS, titles ASO, PPD, chest X-ray or CT scan and, where deemed appropriate, specific autoimmune and infectious serology.es-ES
dc.formatapplication/pdf
dc.languagespa
dc.publisherRevista Médica de Chilees-ES
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dc.sourceRevista Médica de Chile; Vol. 144, núm. 2 (2016): FEBRERO 2016es-ES
dc.source0034-9887
dc.subjectErythema nodosum; Inflammatory bowel diseases; Sarcoidosis; Streptococcal Infections; Tuberculosisen-US
dc.subjectErythema nodosum; Inflammatory bowel diseases; Sarcoidosis; Streptococcal Infections; Tuberculosises-ES
dc.titleERYTHEMA NODOSUM. ANALYSIS OF 91 HOSPITALIZED PATIENTSen-US
dc.titleEritema nodoso: Causas más prevalentes en pacientes que se hospitalizan para estudio, y recomendaciones para el diagnóstico.es-ES
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.typees-ES


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