PROGNOSTIC FACTORS OF ULCERATIVE COLITIS AT THE MOMENT OF DIAGNOSIS
Factores pronósticos en Colitis Ulcerosa de reciente diagnóstico
Author
Pizarro, Gonzalo; Medico Cirujano
Medico Internista
Medico Gatroenterólogo
Fellow Programa Enfermedad Inflamatoria Intestinal Universidad de Chile-Clinica Las Condes
Hospital Barros Lucco Trudeau
Clinica Tabancura
Quera, Rodrigo; Medico Cirujano
Medico Internista
Medico Gatroenterólogo
Clinica Las Condes
Programa Enfermedad Inflamatoria Intestinal
Figueroa, Carolina; Medico Cirujano
Medico Internista
Medico Gatroenterólogo
Clinica Las Condes
Programa Enfermedad Inflamatoria Intestinal
Abstract
The clinical presentation of ulcerative colitis at the moment of diagnosis is variable, and its clinical course is difficult to predict. It can range from a quiescent to a refractory chronic course that may require hospitalization and surgical procedures. It can also have complications such as colorectal cancer. In this review we discuss the role of demographic, clinical, endoscopic, histological and associated factors, which can help to predict the clinical course of the disease at the moment of diagnosis, and to individualize therapy according to this clinical risk. Accurate identification of patients with a newly diagnosed ulcerative colitis who are at high risk of an unfavorable outcome is still a challenge. However, an effective evaluation allows an early diagnosis, a timely and effective treatment. The clinical presentation of ulcerative colitis at the moment of diagnosis is variable, and its clinical course is difficult to predict. It can range from a quiescent to a refractory chronic course that may require hospitalization and surgical procedures. It can also have complications such as colorectal cancer. In this review we discuss the role of demographic, clinical, endoscopic, histological and associated factors, which can help to predict the clinical course of the disease at the moment of diagnosis, and to individualize therapy according to this clinical risk. Accurate identification of patients with a newly diagnosed ulcerative colitis who are at high risk of an unfavorable outcome is still a challenge. However, an effective evaluation allows an early diagnosis, a timely and effective treatment.
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