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Tratamiento quirúrgico del hiperparatiroidismo asociado a insuficiencia renal crónica

SURGICAL TREATMENT OF RENAL HYPERPARATHYROIDISM. EXPERIENCE IN 71 PATIENTS

dc.contributores-ES
dc.contributoren-US
dc.creatorPulgar B, Dahiana; Pontificia universidad Católica de chile
dc.creatorJara C, Aquiles; Pontificia universidad Católica de chile
dc.creatorGonzález V, Gilberto; Pontificia universidad Católica de chile
dc.creatorGonzález D, Hernán; Pontificia universidad Católica de chile
dc.date2015-01-16
dc.date.accessioned2019-11-11T18:26:46Z
dc.date.available2019-11-11T18:26:46Z
dc.identifierhttp://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/view/3879
dc.identifier.urihttps://revistaschilenas.uchile.cl/handle/2250/110820
dc.descriptionBackground: Surgery is an effective method for the management of renal hyperparathyroidism. Aim: To report the clinical presentation and results of surgical treatment of renal hyperparathyroidism. Material and methods: Retrospective analysis of 58 patients aged 46 ± 11 years with secondary hyperparathyroidism (HPT2) and 13 patients aged 53 ± 11 years with tertiary hyperparathyroidism (HPT3), operated at a clinical hospital Results: In 55 cases (77.4%) the indications for surgery were complications of excess parathyroid hormone (PTH) and in 16 patients (22.6%) a failure of medical treatment. Total parathyroidectomy with intraoperative measurement of PTH (PTHop) plus a forearm parathyroid autograft was performed in 54 (93.1%) patients with HPT2 and in all patients with HPT3. PTHop decreased ?75% in 51 patients (88%) with HPT2 and in 9 patients (69.2%) with HPT3, respectively. Cure of the disease was achieved in 52 (89.7%) and 11 (84.6%) patients with HPT2 and 3, respectively. Median follow-up was 41 months. Five (9.6%) patients with HPT2 and two patients (18.2%) with HPT3 had a recurrence of the disease. Conclusions: In patients with renal hyperparathyroidism, the primary indication for surgery was the presence of complications of PTH excess. A drop in PTHop ?75% from baseline predicts healing in 98% and 100% of cases with secondary or tertiary HPT respectively. Surgery was a safe and effective treatment in both groups.es-ES
dc.descriptionBackground: Surgery is an effective method for the management of renal hyperparathyroidism. Aim: To report the clinical presentation and results of surgical treatment of renal hyperparathyroidism. Material and methods: Retrospective analysis of 58 patients aged 46 ± 11 years with secondary hyperparathyroidism (HPT2) and 13 patients aged 53 ± 11 years with tertiary hyperparathyroidism (HPT3), operated at a clinical hospital Results: In 55 cases (77.4%) the indications for surgery were complications of excess parathyroid hormone (PTH) and in 16 patients (22.6%) a failure of medical treatment. Total parathyroidectomy with intraoperative measurement of PTH (PTHop) plus a forearm parathyroid autograft was performed in 54 (93.1%) patients with HPT2 and in all patients with HPT3. PTHop decreased ?75% in 51 patients (88%) with HPT2 and in 9 patients (69.2%) with HPT3, respectively. Cure of the disease was achieved in 52 (89.7%) and 11 (84.6%) patients with HPT2 and 3, respectively. Median follow-up was 41 months. Five (9.6%) patients with HPT2 and two patients (18.2%) with HPT3 had a recurrence of the disease. Conclusions: In patients with renal hyperparathyroidism, the primary indication for surgery was the presence of complications of PTH excess. A drop in PTHop ?75% from baseline predicts healing in 98% and 100% of cases with secondary or tertiary HPT respectively. Surgery was a safe and effective treatment in both groups.en-US
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dc.languagespa
dc.publisherRevista Médica de Chilees-ES
dc.relationhttp://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/view/3879/771
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dc.sourceRevista Médica de Chile; Vol. 143, núm. 2 (2015): FEBRERO 2015es-ES
dc.source0034-9887
dc.subjectHyperparathyroidism, secondary; Parathyroid hormone; Surgeryes-ES
dc.subjectHyperparathyroidism, secondary; Parathyroid hormone; Surgeryen-US
dc.titleTratamiento quirúrgico del hiperparatiroidismo asociado a insuficiencia renal crónicaes-ES
dc.titleSURGICAL TREATMENT OF RENAL HYPERPARATHYROIDISM. EXPERIENCE IN 71 PATIENTSen-US
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.typees-ES


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