RECURRENCE OF GOODPASTURE SYNDROME WITH NEGATIVE ANTIGLOMERULAR BASEMENT ANTIBODIES. REPORT OF ONE CASE

Recurrencia de Síndrome de Goodpasture con negativización de anticuerpos anti-membrana basal glomerular: Caso clínico

Author
Tagle, Rodrigo; Pontificia Universidad Católica de Chile

Arancibia, Trinidad

Fischman, Alexandra

Vázquez, Sebastián

Chahuán, Javier

Méndez, Gonzalo

Huidobro E., Juan Pablo

Full text
http://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/view/3646
Abstract
Goodpasture Syndrome is described as a single episode disease entity. It is diagnosed with the demonstration of antiglomerular basement (anti-GBM) antibodies in plasma or renal tissue. Although the recurrence of anti-GBM disease is rare, it has been reported in up to 3% of cases. Recurrence with negative anti-GBM antibodies in plasma is even less frequent We report a 63 years old male in whom anti-GBM disease recurred without detectable anti-GBM antibodies in plasma, despite having positive antibodies at the onset.
 
Goodpasture Syndrome is described as a single episode disease entity. It is diagnosed with the demonstration of antiglomerular basement (anti-GBM) antibodies in plasma or renal tissue. Although the recurrence of anti-GBM disease is rare, it has been reported in up to 3% of cases. Recurrence with negative anti-GBM antibodies in plasma is even less frequent We report a 63 years old male in whom anti-GBM disease recurred without detectable anti-GBM antibodies in plasma, despite having positive antibodies at the onset.
 
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