RECURRENCE OF GOODPASTURE SYNDROME WITH NEGATIVE ANTIGLOMERULAR BASEMENT ANTIBODIES. REPORT OF ONE CASE
Recurrencia de Síndrome de Goodpasture con negativización de anticuerpos anti-membrana basal glomerular: Caso clínico
Author
Tagle, Rodrigo; Pontificia Universidad Católica de Chile
Arancibia, Trinidad
Fischman, Alexandra
Vázquez, Sebastián
Chahuán, Javier
Méndez, Gonzalo
Huidobro E., Juan Pablo
Abstract
Goodpasture Syndrome is described as a single episode disease entity. It is diagnosed with the demonstration of antiglomerular basement (anti-GBM) antibodies in plasma or renal tissue. Although the recurrence of anti-GBM disease is rare, it has been reported in up to 3% of cases. Recurrence with negative anti-GBM antibodies in plasma is even less frequent We report a 63 years old male in whom anti-GBM disease recurred without detectable anti-GBM antibodies in plasma, despite having positive antibodies at the onset. Goodpasture Syndrome is described as a single episode disease entity. It is diagnosed with the demonstration of antiglomerular basement (anti-GBM) antibodies in plasma or renal tissue. Although the recurrence of anti-GBM disease is rare, it has been reported in up to 3% of cases. Recurrence with negative anti-GBM antibodies in plasma is even less frequent We report a 63 years old male in whom anti-GBM disease recurred without detectable anti-GBM antibodies in plasma, despite having positive antibodies at the onset.
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