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CAUSES AND MANAGEMENT OF SEVERE ACUTE LIVER DAMAGE DURING PREGNANCY

Actualzación en el diagnóstico y manejo del daño hepático agudo grave en el embarazo

dc.contributoren-US
dc.contributores-ES
dc.creatorSepúlveda-Martínez, Alvaro; Hospital Clínico Universidad de Chile
dc.creatorRomero, Carlos; Hospital Clínico Universidad de Chile
dc.creatorJuarez, Guido; Hospital Clínico Universidad de Chile
dc.creatorHasbun, Jorge; Hospital Clínico Universidad de Chile
dc.creatorParra-Cordero, Mauro; Hospital Clínico Universidad de Chile
dc.date2015-04-29
dc.date.accessioned2019-11-11T18:27:12Z
dc.date.available2019-11-11T18:27:12Z
dc.identifierhttp://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/view/3961
dc.identifier.urihttps://revistaschilenas.uchile.cl/handle/2250/111035
dc.descriptionAbnormalities in liver function tests appear in 3% of pregnancies. Severe acute liver damage can be an exclusive condition of pregnancy (dependent or independent of pre-eclampsia) or a concomitant disease. HELLP syndrome and acute fatty liver of pregnancy are the most severe liver diseases associated with pregnancy. Both appear during the third trimester and have a similar clinical presentation. Acute fatty liver may be associated with hypoglycemia and HELLP syndrome is closely linked with pre-eclampsia. Among concomitant conditions, fulminant acute hepatitis caused by medications or virus is the most severe disease. Its clinical presentation may be hyper-acute with neurological involvement and severe coagulation disorders. It has a high mortality and patients should be transplanted. Fulminant hepatic failure caused by acetaminophen overdose can be managed with n-acetyl cysteine. Because of the high fetal mortality rate, the gestational age at diagnosis is crucial.en-US
dc.descriptionAbnormalities in liver function tests appear in 3% of pregnancies. Severe acute liver damage can be an exclusive condition of pregnancy (dependent or independent of pre-eclampsia) or a concomitant disease. HELLP syndrome and acute fatty liver of pregnancy are the most severe liver diseases associated with pregnancy. Both appear during the third trimester and have a similar clinical presentation. Acute fatty liver may be associated with hypoglycemia and HELLP syndrome is closely linked with pre-eclampsia. Among concomitant conditions, fulminant acute hepatitis caused by medications or virus is the most severe disease. Its clinical presentation may be hyper-acute with neurological involvement and severe coagulation disorders. It has a high mortality and patients should be transplanted. Fulminant hepatic failure caused by acetaminophen overdose can be managed with n-acetyl cysteine. Because of the high fetal mortality rate, the gestational age at diagnosis is crucial.es-ES
dc.formatapplication/pdf
dc.languagespa
dc.publisherRevista Médica de Chilees-ES
dc.relationhttp://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/view/3961/1128
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dc.sourceRevista Médica de Chile; Vol. 143, núm. 5 (2015): MAYO 2015es-ES
dc.source0034-9887
dc.subjectAcetaminophen; Fatty liver; HELLP; Liver failure; Pregnancy complications; Syndromeen-US
dc.subjectAcetaminophen; Fatty liver; HELLP; Liver failure; Pregnancy complications; Syndromees-ES
dc.titleCAUSES AND MANAGEMENT OF SEVERE ACUTE LIVER DAMAGE DURING PREGNANCYen-US
dc.titleActualzación en el diagnóstico y manejo del daño hepático agudo grave en el embarazoes-ES
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.typees-ES


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