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IDENTIFICATION OF RISK FACTORS FOR CONGENITAL MALFORMATIONS

Factores de riesgo de ocurrencia y gravedad de malformaciones congénitas.

dc.contributoren-US
dc.contributores-ES
dc.creatorCanals C, Andrea; Instituto de Salud Pública de Chile. Clínica Santa María. Universidad de Chile.
dc.creatorCavada C, Gabriel; Universidad de Chile Universidad de los Andes
dc.creatorNazer H, Julio; Hospital Clínico Universidad de Chile
dc.date2014-10-30
dc.date.accessioned2019-11-11T18:27:15Z
dc.date.available2019-11-11T18:27:15Z
dc.identifierhttp://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/view/3685
dc.identifier.urihttps://revistaschilenas.uchile.cl/handle/2250/111059
dc.descriptionBackground: The relative importance of congenital malformations as a cause of death in the first year of life is increasing along with the control of preventable causes of perinatal mortality. Aim: To identify risk factors for congenital malformations. Patients and methods: Retrospective case-control study of births registered in the database of The Latin American Collaborative Study of Congenital Malformations (ECLAMC), in the period 2001 - 2010. Results: Birth weight and gestational age were significantly lower in cases than controls, behaving as risk factors and associated with a greater severity of congenital malformations. The risk and severity of congenital malformations increased along with mother’s age. Fetal growth retardation, a history of congenital malformations in the family, physical factors and acute illnesses of the mother in the first trimester of pregnancy were also significant risk factors for congenital malformations and their severity. The educational level of the mother was a protective factor for congenital malformations and their severity. Conclusions: Variables previously identified as risk factors for congenital malformations, were significantly related with the occurrence of congenital malformations and their severity.en-US
dc.descriptionBackground: The relative importance of congenital malformations as a cause of death in the first year of life is increasing along with the control of preventable causes of perinatal mortality. Aim: To identify risk factors for congenital malformations. Patients and methods: Retrospective case-control study of births registered in the database of The Latin American Collaborative Study of Congenital Malformations (ECLAMC), in the period 2001 - 2010. Results: Birth weight and gestational age were significantly lower in cases than controls, behaving as risk factors and associated with a greater severity of congenital malformations. The risk and severity of congenital malformations increased along with mother’s age. Fetal growth retardation, a history of congenital malformations in the family, physical factors and acute illnesses of the mother in the first trimester of pregnancy were also significant risk factors for congenital malformations and their severity. The educational level of the mother was a protective factor for congenital malformations and their severity. Conclusions: Variables previously identified as risk factors for congenital malformations, were significantly related with the occurrence of congenital malformations and their severity.es-ES
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dc.languagespa
dc.publisherRevista Médica de Chilees-ES
dc.relationhttp://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/view/3685/544
dc.relationhttp://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/downloadSuppFile/3685/14602
dc.relationhttp://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/downloadSuppFile/3685/14603
dc.relationhttp://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/downloadSuppFile/3685/14604
dc.relationhttp://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/downloadSuppFile/3685/14605
dc.relationhttp://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/downloadSuppFile/3685/14606
dc.relationhttp://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/downloadSuppFile/3685/14607
dc.relationhttp://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/downloadSuppFile/3685/16181
dc.relationhttp://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/downloadSuppFile/3685/16612
dc.sourceRevista Médica de Chile; Vol. 142, núm. 11 (2014): NOVIEMBRE 2014es-ES
dc.source0034-9887
dc.subjectCongenital abnormalities; Hospital, Maternity; Risk factorsen-US
dc.subjectCongenital abnormalities; Hospital, Maternity; Risk factorses-ES
dc.titleIDENTIFICATION OF RISK FACTORS FOR CONGENITAL MALFORMATIONSen-US
dc.titleFactores de riesgo de ocurrencia y gravedad de malformaciones congénitas.es-ES
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.typees-ES


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