Meningomielitis asociadas a infección por herpes virus humano 7. Comunicación de dos casos.
Author
Miranda C, Marcelo; Departamento Neurología, Clínica Las Condes, Santiago. Chile
Torres T, Juan Pablo; Departamento de Pediatría, Unidad de Infectología, Clínica Las Condes, Santiago. Chile.
Larrañaga L, Carmen; Programa de Virología, Instituto de Ciencias Biomédicas, Facultad de Medicina, Universidad de Chile
Acuña L, Guillermo; Departamento de Medicina Interna, Clínica Las Condes
Acuña L, Guillermo; Departamento de Medicina Interna, Clínica Las Condes
Abstract
MENINGOMYELITIS ASSOCIATED WITH INFECTION BY HUMAN HERPES VIRUS 7. REPORT OF TWO CASES Human herpesvirus 7 (HHV-7) may cause encephalomyelitis in immunocompetent adults. We report two patients infected by the virus. A 34 years old male presenting with paraparesis and a sensitive deficiency located in D6 dermatome. Cerebrospinal fluid had 35 while blood cells per mm3 and 75 mg protein per dl. A PCR-microarray examination was positive for HHV-7. The patient was treated with prednisolone and ganciclovir with full recovery. A 27 years old male presenting with headache, fever and diarrhea. Cerebrospinal fluid analysis showed 160 cells per mm3 and 75 mg protein per dl. Viral RNA detection was positive for HHV-7. The patient was managed with analgesia and rest and was discharged with the diagnosis of viral meningitis. Our comunication supports the notion that HHV-7 may be considered as pathogen factor in humans, even in immunocompetent ones.