Show simple item record

Daño arterial asociado a la enfermedad renal crónica: evaluación mediante técnicas de laboratorio no invasivo en pacientes hemodializados.

dc.contributorPROYECTO FONDO AYUDA INVESTIGACION UANDES MED 02-006es-ES
dc.creatorEspinoza, Francisco; Facultad de Medicina, Universidad de los Andes
dc.creatorKunstmann, Sonia; Facultad de Medicina, Universidad de los AndesDepartamento de Enfermedades Cardiovasculares, Clínica Las Condes
dc.creatorMichea, Luis; Facultad de Medicina, Universidad de los Andes
dc.creatorMarusic, Elisa T; Facultad de Medicina, Universidad de los Andes
dc.creatorVukusich, Antonio; Facultad de Medicina, Universidad de los AndesDepartamento de Nefrología, Clínica Dávila
dc.date2012-01-10
dc.date.accessioned2019-11-11T18:27:23Z
dc.date.available2019-11-11T18:27:23Z
dc.identifierhttp://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/view/1198
dc.identifier.urihttps://revistaschilenas.uchile.cl/handle/2250/111101
dc.descriptionMENT OF ARTERIAL DAMAGE BY NONINVASIVE PERIPHERAL ARTERIAL TONOMETRY IN NON-DIABETIC HEMODIALYSIS PATIENTSBackground: Hemodialysis patients (HD) display high rates of cardiac disease and mortality.  The cardiovascular morbidity and mortality of HD patients is attributable in a significant proportion to endothelial dysfunction, arterial stiffness, and vascular calcifications. Aim: To measure vascular reactivity in HD subjects and compare them with healthy volunteers. Material and methods:  Forty eight non diabetic patients aged 58 ± 4.6 years (29 males) on hemodialysis for a mean lapse of  4.8 years were studied. Arterial stiffness was measured in the radial artery. Pulse wave velocity was measured by noninvasive peripheral arterial tonometry in carotid and femoral arteries.  Endothelial function was assessed, measuring  reactive hyperemia response after a 5 min period of ischemia.  As a control, all  values were also measured in age and gender-matched healthy volunteers.  Results: Arterial stiffness was significantly higher in HD patients than controls (23.9 ± 3.3 and 18.4 ± 3.4% respectively, p < 0.05). HD subjects had an increased pulse wave velocity (10.0 ± 0.8  and 7.6 ± 0.9 m/s respectively, p < 0.05). A reduction in the change in pulse amplitude pressure, as a measure of arterial dysfunction, was only observed in male patients (1.7 ± 0.4 and 2.7 ± 0.4 respectively P < 0.01). Conclusions: Noninvasive assessment of peripheral vascular function may be useful for the identification of patients at risk for late cardiac events.es-ES
dc.languagees
dc.publisherRevista Médica de Chilees-ES
dc.relationhttp://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/downloadSuppFile/1198/1479
dc.relationhttp://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/downloadSuppFile/1198/3617
dc.relationhttp://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/downloadSuppFile/1198/3618
dc.relationhttp://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/downloadSuppFile/1198/3619
dc.relationhttp://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/downloadSuppFile/1198/3621
dc.relationhttp://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/downloadSuppFile/1198/3622
dc.relationhttp://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/downloadSuppFile/1198/3623
dc.relationhttp://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/downloadSuppFile/1198/3624
dc.relationhttp://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/downloadSuppFile/1198/4792
dc.sourceRevista Médica de Chile; Vol. 140, núm. 2 (2012): FEBRERO 2012es-ES
dc.source0034-9887
dc.subjectDiagnostic techniques, cardiovascular; Renal insufficiency; Vascular diseaseses-ES
dc.titleDaño arterial asociado a la enfermedad renal crónica: evaluación mediante técnicas de laboratorio no invasivo en pacientes hemodializados.es-ES
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.typees-ES


This item appears in the following Collection(s)

Show simple item record