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Diferencia veno-arterial de dióxido de carbono como predictor de gasto cardiaco disminuido en modelo experimental.

dc.contributorEstudio financiado por proyectos Fondecyt 11075041 y Sociedad Chilena de Pediatría 2008.es-ES
dc.creatorDíaz, Franco; Medicina Intensiva Infantil. Facultad de Medicina Clínica Alemana Universidad del Desarrollo. Hospital Padre Hurtado
dc.creatorDonoso, Alejandro; Medicina Intensiva Infantil. Facultad de Medicina Clínica Alemana Universidad del Desarrollo. Hospital Padre Hurtado
dc.creatorCarvajal, Cristóbal; Residente Becario de Cirugía. Facultad de Medicina Clínica Alemana Universidad del Desarrollo. Hospital Padre Hurtado
dc.creatorSalomón, Tatiana; Enfermería Intensiva Infantil. Facultad de Medicina Clínica Alemana Universidad del Desarrollo. Hospital Padre Hurtado
dc.creatorTorres, María; Licenciado en Ingeniería en Biotecnología MolecularFacultad de Medicina Clínica Alemana Universidad del Desarrollo. Hospital Padre Hurtado
dc.creatorErranz, Benjamín; Licenciado en Ingeniería en Biotecnología MolecularFacultad de Medicina Clínica Alemana Universidad del Desarrollo. Hospital Padre Hurtado
dc.creatorCruces, Pablo; Medicina Intensiva Infantil. Universidad del Desarrollo. Hospital Padre Hurtado
dc.date2011-12-16
dc.date.accessioned2019-11-11T18:27:42Z
dc.date.available2019-11-11T18:27:42Z
dc.identifierhttp://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/view/1403
dc.identifier.urihttps://revistaschilenas.uchile.cl/handle/2250/111264
dc.descriptionVENO-ARTERIAL PCO2 DIFFERENCE TO PREDICT LOW CARDIAC OUTPUT IN AN EXPERIMENTAL PIGLET MODEL Background: Cardiac output (CO) measurement is not a standard of care for critically ill children, but it can be estimated by indirect methods such as veno-arterial pCO2 difference (?VACO2). Aim: To determine the correlation between CO and ?VACO2 and evaluate the usefulness of ?VACO2 in the diagnosis of low CO in an experimental pediatric model. Material and methods: Thirty piglets weighing 4.8±0.35 kg, were anesthetized and monitored with transpulmonary thermodilution. Lung injury was induced with tracheal instillation of Tween 20®. Serial measurements of central venous and arterial blood gases, as well as CO, were obtained at baseline, 1, 2 and 4 h after lung injury induction. Low cardiac output (LCO) was defined as CO lower than 2.5 L/min/m2.  Results: There was an inverse correlation between CO and ?VACO2 (r= -0.36, p< 0.01).  ?VACO2 was 14 ± 8 mmHg in LCO state and 8 ± 6 mmHg when this condition was not present (p< 0.01).  Area under the receiver operating characteristic (ROC) curves of ?VACO2 and LCO state was 0.78 (0.68-0.86). The best cut-point was 8.9 mmHg to determine LCO with a sensibility 0.78, specificity 0.7, positive predictive value 0.27 and negative predictive value 0.96. Conclusions: In this model there was an inverse correlation between ?VACO2 and CO. The best cutoff value to discard LCO was ?VACO2 of 8.9 mmHg, indicating that under this value the presence of LCO is very unlikely.  es-ES
dc.languagees
dc.publisherRevista Médica de Chilees-ES
dc.relationhttp://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/downloadSuppFile/1403/2213
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dc.relationhttp://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/downloadSuppFile/1403/3961
dc.relationhttp://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/downloadSuppFile/1403/3962
dc.relationhttp://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/downloadSuppFile/1403/3963
dc.relationhttp://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/downloadSuppFile/1403/3964
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dc.relationhttp://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/downloadSuppFile/1403/3966
dc.sourceRevista Médica de Chile; Vol. 140, núm. 1 (2012): ENERO 2012es-ES
dc.source0034-9887
dc.subjectBlood gas monitoring; Carbon Dioxide; Critical Care; Hemodynamics; Outputes-ES
dc.titleDiferencia veno-arterial de dióxido de carbono como predictor de gasto cardiaco disminuido en modelo experimental.es-ES
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.typees-ES


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