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SUSTAINED UPGAZE IN A PATIENT WHO INGESTED HIGH DOSES OF BUPROPION. REPORT OF ONE CASE

Supraversión de la mirada en intoxicación mortal por bupropión

dc.contributoren-US
dc.contributores-ES
dc.creatorCartier R, Luis; Universidad de Chile
dc.creatorRomero O, Cristian; Universidad de Chile
dc.creatorPérez P, Gerardo; Universidad de Chile
dc.date2018-05-29
dc.date.accessioned2019-11-11T18:27:52Z
dc.date.available2019-11-11T18:27:52Z
dc.identifierhttp://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/view/6311
dc.identifier.urihttps://revistaschilenas.uchile.cl/handle/2250/111330
dc.descriptionUpgaze or sustained elevation of the eyes, is an alteration of ocular motility initially described in hypoxic coma. We report a 65-year-old woman admitted with hypotension and alteration of sensorium due to the ingestion of 9.5 g of Bupropion. She presented two seizures of short duration, without epileptic activity on the EEG. She had a persistent asynchronous myoclonus in extremities, tachycardia and prolonged Q-t. She suffered a cardiac arrest caused by asystole, which recovered quickly in five minutes. At that moment, upgaze appeared, associated with a persistent ocular opening, which persisted for days, but finally disappeared, without remission of coma. A magnetic resonance imaging done at the eighth day, showed hyperintensity of the oval center and corpus callosum which disappeared in a new imaging study done 30 days later, where images of hypoxia in the basal nuclei and cortex appeared. The patient died forty seven days after admission. Up-gaze is an ominous oculomotor alteration linked to an important but incomplete damage in the cerebral cortex, a condition that perverts some sequences of the ocular opening, reversing the Bell phenomenon and producing eyelid retraction.en-US
dc.descriptionUpgaze or sustained elevation of the eyes, is an alteration of ocular motility initially described in hypoxic coma. We report a 65-year-old woman admitted with hypotension and alteration of sensorium due to the ingestion of 9.5 g of Bupropion. She presented two seizures of short duration, without epileptic activity on the EEG. She had a persistent asynchronous myoclonus in extremities, tachycardia and prolonged Q-t. She suffered a cardiac arrest caused by asystole, which recovered quickly in five minutes. At that moment, upgaze appeared, associated with a persistent ocular opening, which persisted for days, but finally disappeared, without remission of coma. A magnetic resonance imaging done at the eighth day, showed hyperintensity of the oval center and corpus callosum which disappeared in a new imaging study done 30 days later, where images of hypoxia in the basal nuclei and cortex appeared. The patient died forty seven days after admission. Up-gaze is an ominous oculomotor alteration linked to an important but incomplete damage in the cerebral cortex, a condition that perverts some sequences of the ocular opening, reversing the Bell phenomenon and producing eyelid retraction.es-ES
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dc.languagespa
dc.publisherRevista Médica de Chilees-ES
dc.relationhttp://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/view/6311/4013
dc.relationhttp://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/downloadSuppFile/6311/31774
dc.relationhttp://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/downloadSuppFile/6311/31775
dc.relationhttp://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/downloadSuppFile/6311/31777
dc.relationhttp://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/downloadSuppFile/6311/31778
dc.relationhttp://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/downloadSuppFile/6311/31779
dc.relationhttp://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/downloadSuppFile/6311/32264
dc.sourceRevista Médica de Chile; Vol. 146, núm. 5 (2018): MAYO 2018es-ES
dc.source0034-9887
dc.subjectBupropion; Coma; Hypoxia; Leukoencephalopathiesen-US
dc.subjectBupropion; Coma; Hypoxia; Leukoencephalopathieses-ES
dc.titleSUSTAINED UPGAZE IN A PATIENT WHO INGESTED HIGH DOSES OF BUPROPION. REPORT OF ONE CASEen-US
dc.titleSupraversión de la mirada en intoxicación mortal por bupropiónes-ES
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.typees-ES


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