NECROTIZING TRACHEOBRONCHIAL ASPERGILLOSIS IN AN IMMUNOSUPPRESSED PATIENT. REPORT OF ONE CASE
Aspergilosis Traqueobronquial Pseudomembranosa Necrotizante, en Paciente Crítico
Author
Andresen H, Max; Pontificia Universidad catolica de Chile
Venegas, Carmen Paz; departamento de enfermedades respiratorias uc
Vega, Claudia; Departamento de medicina intensiva
Aravena, Carlos; departamento de enfermedades respiratorias uc
Andresen V, Max; Facultad de medicina PUC
Abstract
Necrotizing tracheobronchitis due to Aspergillus spp is a rare form of invasive aspergillosis. This infection is limited to or predominant in the bronchial tree. The clinical evolution is gradual: from mild non-specific manifestations of acute tracheobronchitis to severe acute respiratory insufficiency determined by a bronchial obstruction syndrome. We report a 38 years old female with systemic lupus erythematosus treated with methylprednisolone and cyclophosphamide. She developed an invasive aspergillosis, severe respiratory failure with predominant tracheobronchial damage and upper respiratory complications. Necrotizing tracheobronchitis due to Aspergillus spp is a rare form of invasive aspergillosis. This infection is limited to or predominant in the bronchial tree. The clinical evolution is gradual: from mild non-specific manifestations of acute tracheobronchitis to severe acute respiratory insufficiency determined by a bronchial obstruction syndrome. We report a 38 years old female with systemic lupus erythematosus treated with methylprednisolone and cyclophosphamide. She developed an invasive aspergillosis, severe respiratory failure with predominant tracheobronchial damage and upper respiratory complications.