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DIAGNOSTIC ACCURACY OF SERUM PROTEIN ELECTROPHORESIS AND FREE LIGHT CHAIN MEASUREMENTS FOR MONOCLONAL GAMMOPATHIES

Sensibilidad diagnóstica en gammapatías monoclonales y utilidad de las cadenas livianas libres en suero: realidad en un hospital público chileno.

dc.contributoren-US
dc.contributores-ES
dc.creatorPeña Ojeda, Camila
dc.creatorVoisin Cornejo, Javier
dc.creatorPeralta Bondi, Alexis
dc.creatorbalboa charcas, Viviana
dc.creatorOrtiz soto, Manuela
dc.creatorDelgado, Florencia
dc.date2018-01-19
dc.date.accessioned2019-11-11T18:28:08Z
dc.date.available2019-11-11T18:28:08Z
dc.identifierhttp://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/view/6106
dc.identifier.urihttps://revistaschilenas.uchile.cl/handle/2250/111475
dc.descriptionBackground: International guidelines suggest a screening panel for monoclonal gammopathies that contains serum protein electrophoresis (SPE), free light chain (FLC) measurements and immunofixation. This combination provides the possibility of a timely accurate diagnosis. Aim: To evaluate the sensibility of a simple screening panel (SPE + FLC). Material and methods: We analyzed 75 serum samples of patients with a monoclonal gammopathy. Results: The sensitivity and specificity of the combination of SPE + FLC for the diagnosis of monoclonal gammopathy were 95% (95% confidence intervals 89-99) and 99% (95% confidence intervals 96-100), respectively. Conclusions: We were able to validate the international recommendations about the diagnostic accuracy of this simple combination of two tests in serum for monoclonal gammopathy.en-US
dc.descriptionBackground: International guidelines suggest a screening panel for monoclonal gammopathies that contains serum protein electrophoresis (SPE), free light chain (FLC) measurements and immunofixation. This combination provides the possibility of a timely accurate diagnosis. Aim: To evaluate the sensibility of a simple screening panel (SPE + FLC). Material and methods: We analyzed 75 serum samples of patients with a monoclonal gammopathy. Results: The sensitivity and specificity of the combination of SPE + FLC for the diagnosis of monoclonal gammopathy were 95% (95% confidence intervals 89-99) and 99% (95% confidence intervals 96-100), respectively. Conclusions: We were able to validate the international recommendations about the diagnostic accuracy of this simple combination of two tests in serum for monoclonal gammopathy.es-ES
dc.formatapplication/pdf
dc.languagespa
dc.publisherRevista Médica de Chilees-ES
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dc.sourceRevista Médica de Chile; Vol. 146, núm. 1 (2018): ENERO 2018es-ES
dc.source0034-9887
dc.subjectDiagnosis; Multiple Myeloma; Paraproteinemiasen-US
dc.subjectDiagnosis; Multiple Myeloma; Paraproteinemiases-ES
dc.titleDIAGNOSTIC ACCURACY OF SERUM PROTEIN ELECTROPHORESIS AND FREE LIGHT CHAIN MEASUREMENTS FOR MONOCLONAL GAMMOPATHIESen-US
dc.titleSensibilidad diagnóstica en gammapatías monoclonales y utilidad de las cadenas livianas libres en suero: realidad en un hospital público chileno.es-ES
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.typees-ES


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