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DRESS SYNDROME. REPORT OF NINE CASES

Reacción por drogas con eosinofiia y síntomas sistémicos (Síndrome de DRESS). Estudio retrospectivo de nueve casos

dc.contributoren-US
dc.contributorServicio de Dermatología, Hospital Universitario "Dr. José E. González"es-ES
dc.creatorOcampo-Garza, Jorge; Servicio de Dermatología Hospital Universitario "Dr. José E. González"
dc.creatorOcampo-Garza, Sonia Sofía; Servicio de Dermatología Hospital Universitario "Dr. José E. González"
dc.creatorMartínez-Villarreal, José Dario; Departamento de Medicina Interna Hospital Universitario "Dr. José E. González"
dc.creatorBarbosa-Moreno, Laura Elena; Servicio de Dermatología Hospital Universitario "Dr. José E. González"
dc.creatorGuerrero-González, Guillermo Antonio; Servicio de Dermatología Hospital Universitario "Dr. José E. González"
dc.creatorOcampo-Candiani, Jorge; Servicio de Dermatología Hospital Universitario "Dr. José E. González"
dc.date2015-04-29
dc.date.accessioned2019-11-11T18:28:15Z
dc.date.available2019-11-11T18:28:15Z
dc.identifierhttp://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/view/4002
dc.identifier.urihttps://revistaschilenas.uchile.cl/handle/2250/111486
dc.descriptionBackground: DRESS Syndrome (Drug Reaction with Eosinophilia and Systemic Symptoms) is an uncommon disease caused by drugs. It is characterized by a polymorphic disseminated eruption with fever and multiple organ dysfunction. Aim: To report the etiology, characteristics, treatment, prognosis, and follow up of patients with DRESS Syndrome admitted to a clinical hospital. Material and methods: Review of medical records of patients admitted for drug reactions, selecting those patients complying with clinical criteria for DRESS Syndrome. Drugs used during three months prior to the onset of symptoms were evaluated as possible causes of the disease. Results: Nine patients aged 16 to 68 years (six males) complied with the clinical criteria for the disease. The causative medications were carbamazepine in three patients, phenytoin in three, antituberculous drugs in two and amoxicillin in one. All were treated with systemic steroids with a complete clinical resolution. Conclusions: DRESS syndrome is usually underdiagnosed and has a good response to systemic steroids.en-US
dc.descriptionBackground: DRESS Syndrome (Drug Reaction with Eosinophilia and Systemic Symptoms) is an uncommon disease caused by drugs. It is characterized by a polymorphic disseminated eruption with fever and multiple organ dysfunction. Aim: To report the etiology, characteristics, treatment, prognosis, and follow up of patients with DRESS Syndrome admitted to a clinical hospital. Material and methods: Review of medical records of patients admitted for drug reactions, selecting those patients complying with clinical criteria for DRESS Syndrome. Drugs used during three months prior to the onset of symptoms were evaluated as possible causes of the disease. Results: Nine patients aged 16 to 68 years (six males) complied with the clinical criteria for the disease. The causative medications were carbamazepine in three patients, phenytoin in three, antituberculous drugs in two and amoxicillin in one. All were treated with systemic steroids with a complete clinical resolution. Conclusions: DRESS syndrome is usually underdiagnosed and has a good response to systemic steroids.es-ES
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dc.languagespa
dc.publisherRevista Médica de Chilees-ES
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dc.sourceRevista Médica de Chile; Vol. 143, núm. 5 (2015): MAYO 2015es-ES
dc.source0034-9887
dc.subjectDexamethasone; Drug eruptions; Drug hypersensitivity syndromeen-US
dc.subjectDexamethasone; Drug eruptions; Drug hypersensitivity syndromees-ES
dc.titleDRESS SYNDROME. REPORT OF NINE CASESen-US
dc.titleReacción por drogas con eosinofiia y síntomas sistémicos (Síndrome de DRESS). Estudio retrospectivo de nueve casoses-ES
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.typees-ES


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