Utilidad del estudio PET con FDG en la evaluación de sarcomas de diverso origen y de tumores no-sarcomas no epiteliales (NSNE)
Author
Massardo, Teresa; Sección Medicina Nuclear, Departamento de Medicina, Hospital Clínico Universidad de Chile
Jofre, María Josefina; Centro PET de Imágenes Moleculares, Hospital Militar de Santiago, HOSMIL Chile.
Sierralta, María Paulina; Centro PET de Imágenes Moleculares, Hospital Militar de Santiago, HOSMIL Chile.
Canessa, José; Servicio de Medicina Nuclear, Hospital Dirección de Previsión de Carabineros de Chile, DIPRECA
Castro, Gabriel; Sección Medicina Nuclear, Departamento de Medicina, Hospital Clínico Universidad de Chile
Berrocal, Isabel; Sección Medicina Nuclear, Departamento de Medicina, Hospital Clínico Universidad de Chile
Gallegos, Iván; Departamento Anatomía Patológica, Hospital Clínico Universidad de Chile
Abstract
POSITRON EMISSION TOMOGRAPHY WITH FLUORINE-DEOXYGLUCOSE IN SARCOMAS AND NON-SARCOMA NON-EPITHELIAL TUMORS. Background: The usefulness of positron emission tomography (PET) with fluorine-deoxyglucose (FDG) in sarcomas and non-sarcoma non-epithelial (NSNE) tumors is not clearly defined Aim: To report a Chilean experience with NSNE tumors evaluated using PET with FDG. Material and methods: Retrospective review of the database of a PET laboratory. Demographic data, indications and metabolic findings were compared with conventional imaging in 88 adults and children with diverse bone and soft tissue sarcomas as well as 24 gastrointestinal stromal tumors (GIST), 6 pleural malignant mesotheliomas in adults, and 9 medulloblastomas in children. Results: FDG showed good concordance with conventional imaging in NSNE tumors. It was helpful for staging, restaging, follow-up after treatment and for the detection of new not previously suspected lesions. Conclusions: PET with FDG could have a prognostic role and help in patient management, mainly in musculoskeletal and high grade or less differentiated sarcomas. In GIST, it was a good tool for immunotherapy control.
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