CHANGES IN THE CLINICAL PRESENTATION OF INFLUENZA A H1N1pdm09 AFTER THE PANDEMIC
Cambios en la presentación clínica de la influenza A H1N1pdm09 después de la pandemia
Author
Riquelme, Raúl; Universidad San Sebastián sede Patagonia
Hospital de Puerto Montt
Rioseco, Maria Luisa; Universidad San Sebastián sede Patagonia
Hospital de Puerto Montt
Velásquez, Karen; Universidad San Sebastián sede Patagonia
Hospital de Puerto Montt
Campos, Fernando; Universidad San Sebastián sede Patagonia
Hospital de Puerto Montt
Gayán, Benjamín; Universidad San Sebastián sede Patagonia
Hospital de Puerto Montt
Medina Aroca, Cristian; Hospital de Puerto Montt
Inzunza, Carlos; Universidad San Sebastián sede Patagonia
Hospital de Puerto Montt
Riquelme, Mauricio; Universidad San Sebastián sede Patagonia
Hospital de Puerto Montt
Abstract
Background: After the 2009 influenza pandemic the H1N1pdm09 strain circulate seasonally. In 2015, Puerto Montt Hospital in Chile faced a simultaneous outbreak of both seasonal H3N2 and H1N1pdm09 influenza A (IA). Aim: To evaluate the clinical differences between the two viral strains and recent changes in the behavior of H1N1pdm09 IA. Material and methods: We set up a retrospective study including every adult hospitalized in Puerto Montt Hospital in 2015 due to IA, confirmed by reverse transcription polymerase chain reaction. We compared epidemiological data, clinical presentation, complications, and the outcome of patients with H1N1pdm09 versus those with seasonal influenza. In parallel, we compared 62 cases of thatH1N1 IA from 2015 with 100 cases who were hospitalized and analyzed in 2009. Results: Between July and October 2015, 119 adults with confirmed IA were hospitalized. From 2009 to 2015, the mean age of patients with IAH1N1pdm09 increased from 40.4 ± 17 to 58.8 ± 16 years (p Background: After the 2009 influenza pandemic the H1N1pdm09 strain circulate seasonally. In 2015, Puerto Montt Hospital in Chile faced a simultaneous outbreak of both seasonal H3N2 and H1N1pdm09 influenza A (IA). Aim: To evaluate the clinical differences between the two viral strains and recent changes in the behavior of H1N1pdm09 IA. Material and methods: We set up a retrospective study including every adult hospitalized in Puerto Montt Hospital in 2015 due to IA, confirmed by reverse transcription polymerase chain reaction. We compared epidemiological data, clinical presentation, complications, and the outcome of patients with H1N1pdm09 versus those with seasonal influenza. In parallel, we compared 62 cases of thatH1N1 IA from 2015 with 100 cases who were hospitalized and analyzed in 2009. Results: Between July and October 2015, 119 adults with confirmed IA were hospitalized. From 2009 to 2015, the mean age of patients with IAH1N1pdm09 increased from 40.4 ± 17 to 58.8 ± 16 years (p
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