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SYNTHESIS AND ANTIFUNGAL ACTIVITY OF DIARYL HYDRAZONES FROM 2,4 DINITROPHENYLHYDRAZINE

dc.creatorOrtiz, Sergio
dc.creatorNelson, Ronald
dc.creatorKesternich, Víctor
dc.creatorPérez-Fehrmann, Marcia
dc.creatorChristen, Philippe
dc.creatorMarcourt, Laurence
dc.date2016-09-10
dc.date.accessioned2019-11-13T15:11:23Z
dc.date.available2019-11-13T15:11:23Z
dc.identifierhttp://www.jcchems.com/index.php/JCCHEMS/article/view/83
dc.identifier.urihttps://revistaschilenas.uchile.cl/handle/2250/112518
dc.descriptionA new series of diarylhydrazones derived from 2,4-dinitrophenylhydrazine were synthesized via condensation with aromatic aldehydes whose structures have been determined by mass spectrometry, infrared spectroscopy, and nuclear magnetic resonance spectra. Yields were 50–99%. All compounds were screened in vitro for their antifungal activity. Preliminary results indicated that compounds 3g and 3h exhibited promising antifungal potency. Understanding of the structure of these compounds establishes a preliminary structure-activity relationship to form the basis of further investigation. en-US
dc.formatapplication/pdf
dc.languageeng
dc.publisherSociedad Chilena de Químicaen-US
dc.relationhttp://www.jcchems.com/index.php/JCCHEMS/article/view/83/69
dc.rightsCopyright (c) 2017 Sergio Ortiz, Ronald Nelson, Víctor Kesternich, Marcia Pérez-Fehrmann, Philippe Christen, Laurence Marcourten-US
dc.rightshttps://creativecommons.org/licenses/by-nc-sa/4.0en-US
dc.sourceJournal of the Chilean Chemical Society; Vol 61 No 3 (2016): Journal of the Chilean Chemical Societyen-US
dc.source0717-9707
dc.source0717-9324
dc.subjectAntifungal Activityen-US
dc.subjectDiarylhydrazonesen-US
dc.subjectSchiff basesen-US
dc.titleSYNTHESIS AND ANTIFUNGAL ACTIVITY OF DIARYL HYDRAZONES FROM 2,4 DINITROPHENYLHYDRAZINEen-US
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion


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