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dc.creatorRoldán, Nicole
dc.creatorSalinas Parra, Nicolás
dc.creatorGonzalez, Alexis A.
dc.creatorCifuentes Araneda, Flavia
dc.creatorArias, Helen
dc.creatorBravo, Manuel
dc.creatorQuiroz, Waldo
dc.date2016-12-10
dc.date.accessioned2019-11-13T15:11:25Z
dc.date.available2019-11-13T15:11:25Z
dc.identifierhttp://www.jcchems.com/index.php/JCCHEMS/article/view/114
dc.identifier.urihttps://revistaschilenas.uchile.cl/handle/2250/112546
dc.descriptionIn this study a method was implemented for the determination of total As and its inorganic species in human urine by HPLC-HG-AFS. The method was applied to workers occupationally exposed to mining and thermoelectric operations. Results shows high levels of As in urine up to 188±4 μg L-1 and As(III) up to 10.7±0.6 μg L-1. Toxic effects of As(III) at the concentration levels founded in human urine were evaluated over the morphology and fibrosis of renal epithelial collecting duct cells in vitro. Our results suggest that urinary tract epithelial renal tubular cells exposed to this concentration of As(III) result in epithelial-mesenchymal transition. en-US
dc.formatapplication/pdf
dc.languageeng
dc.publisherSociedad Chilena de Químicaen-US
dc.relationhttp://www.jcchems.com/index.php/JCCHEMS/article/view/114/99
dc.rightsCopyright (c) 2017 Nicole Roldán, Nicolás Salinas Parra, Alexis A. Gonzalez, Flavia Cifuentes Araneda, Helen Arias, Manuel Bravo, Waldo Quirozen-US
dc.rightshttps://creativecommons.org/licenses/by-nc-sa/4.0en-US
dc.sourceJournal of the Chilean Chemical Society; Vol 61 No 4 (2016): Journal of the Chilean Chemical Societyen-US
dc.source0717-9707
dc.source0717-9324
dc.subjectArsenicen-US
dc.subjectSpeciationen-US
dc.subjectRenal cellsen-US
dc.subjectUrineen-US
dc.subjectToxic effectsen-US
dc.titleIMPLEMENTATION OF AN ANALYTICAL METHOD FOR THE DETERMINATION OF INORGANIC ARSENIC SPECIES IN OCCUPATIONALLY EXPOSED HUMAN URINE SAMPLES AND ITS TOXIC EFFECTS ON EPITHELIAL CELLS OF RENAL COLLECTING TUBULEen-US
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion


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