EFFECTS OF PHYSICAL AND CHEMICAL MODIFICATION ON BIOLOGICAL ACTIVITIES OF CHITOSAN/ CARBOXYMETHYLCELLUSE BASED HYDROGELS

Benghanem, Saida; Chetouani, Asma; Elkolli, Meriem; Bounekhel, Mahmoud; Benachour, Djafar

dc.creator	Benghanem, Saida
dc.creator	Chetouani, Asma
dc.creator	Elkolli, Meriem
dc.creator	Bounekhel, Mahmoud
dc.creator	Benachour, Djafar
dc.date	2017-06-05
dc.date.accessioned	2019-11-13T15:11:33Z
dc.date.available	2019-11-13T15:11:33Z
dc.identifier	http://www.jcchems.com/index.php/JCCHEMS/article/view/152
dc.identifier.uri	https://revistaschilenas.uchile.cl/handle/2250/112577
dc.description	Hydrogels network based on carboxymethylcellulose (CMC) and chitosan (CS), CC1 and CC2, have been prepared respectively in the presence or without the crosslinking agents [(N-hydroxysuccinimide (NHS)/N,N’-dicyclohexylcarbodiimide (DCC)] and characterized by FT-IR.The swelling behavior in distilled water at 25°C and biological activities have been investigated. CC1 hydrogel revealed higher potential swelling than CC2. Hydrogels showed to possess an important antioxidant activity equal to 66.67% for CC1 and 57.27% for CC2, to scavenge hydroxyl radicals at 2mg/mL. And the values of their reducing power were approximately 53% and 57%.From the hemolytic potential test the obtained materials were hemo-compatible. The anti-inflammatory activity exhibited that hydrogels were able to protect albumin from denaturation.	en-US
dc.format	application/pdf
dc.language	eng
dc.publisher	Sociedad Chilena de Química	en-US
dc.relation	http://www.jcchems.com/index.php/JCCHEMS/article/view/152/130
dc.rights	Copyright (c) 2017 Saida Benghanem, Asma Chetouani, Meriem Elkolli, Mahmoud Bounekhel, Djafar Benachour	en-US
dc.rights	https://creativecommons.org/licenses/by-nc-sa/4.0	en-US
dc.source	Journal of the Chilean Chemical Society; Vol 62 No 1 (2017): Journal of the Chilean Chemical Society	en-US
dc.source	0717-9707
dc.source	0717-9324
dc.subject	Chitosan	en-US
dc.subject	Carboxymethylcellulose	en-US
dc.subject	Hydrogels	en-US
dc.subject	Swelling	en-US
dc.subject	Biological activities	en-US
dc.title	EFFECTS OF PHYSICAL AND CHEMICAL MODIFICATION ON BIOLOGICAL ACTIVITIES OF CHITOSAN/ CARBOXYMETHYLCELLUSE BASED HYDROGELS	en-US
dc.type	info:eu-repo/semantics/article
dc.type	info:eu-repo/semantics/publishedVersion

This item appears in the following Collection(s)

Journal of the Chilean Chemical Society
[0-9]{4}

Show simple item record