| dc.creator | Macías-Villamizar, Víctor | |
| dc.creator | Cuca-Suárez, Luís | |
| dc.date | 2017-06-16 | |
| dc.date.accessioned | 2019-11-13T15:11:34Z | |
| dc.date.available | 2019-11-13T15:11:34Z | |
| dc.identifier | http://www.jcchems.com/index.php/JCCHEMS/article/view/179 | |
| dc.identifier.uri | https://revistaschilenas.uchile.cl/handle/2250/112588 | |
| dc.description | In the genus Nectandra, the presence of certain types of secondary metabolites has been determined, including sesquiterpenes, phytosterols, polyalcohols, arylpropionic acid derivatives, flavonols, arylpropanoids, furofuran lignans, dihydrobenzofuran neolignans [1], and certain norlignans [2], alkaloids [3], tannins [4], diterpenes [5], and components of essential oils [6]. However, the chemotaxonomic characteristics are determined by the presence of lignan-type compounds [7]. The ultimate goal of structural modification of natural products is to obtain new drugs [8]. In that sense, there is a growing interest in lignans and their synthetic derivatives due to applications in cancer chemotherapy and various other pharmacological effects [9]. This work corresponds to the first report of this type of structural modification of lignan compounds (7,7’-epoxylignans and diaryldimethylbutane lignans) isolated from Nectandra species. Therefore, this work can be used as a starting point for structure-activity relationship studies. | en-US |
| dc.format | application/pdf | |
| dc.language | eng | |
| dc.publisher | Sociedad Chilena de Química | en-US |
| dc.relation | http://www.jcchems.com/index.php/JCCHEMS/article/view/179/141 | |
| dc.rights | Copyright (c) 2017 Víctor Macías-Villamizar, Luís Cuca-Suárez | en-US |
| dc.rights | https://creativecommons.org/licenses/by-nc-sa/4.0 | en-US |
| dc.source | Journal of the Chilean Chemical Society; Vol 62 No 2 (2017): Journal of the Chilean Chemical Society | en-US |
| dc.source | 0717-9707 | |
| dc.source | 0717-9324 | |
| dc.title | STRUCTURAL MODIFICATION OF LIGNAN COMPOUNDS ISOLATED FROM NECTANDRA SPECIES (LAURACEAE) | en-US |
| dc.type | info:eu-repo/semantics/article | |
| dc.type | info:eu-repo/semantics/publishedVersion | |
