| dc.creator | Potluri, Haritha | |
| dc.creator | Rao Battula, Sreenivasa | |
| dc.creator | Yeturu, Sunandamma | |
| dc.date | 2017-06-16 | |
| dc.date.accessioned | 2019-11-13T15:11:35Z | |
| dc.date.available | 2019-11-13T15:11:35Z | |
| dc.identifier | http://www.jcchems.com/index.php/JCCHEMS/article/view/192 | |
| dc.identifier.uri | https://revistaschilenas.uchile.cl/handle/2250/112600 | |
| dc.description | A simple and precise stability indicating RP-HPLC method was developed for simultaneous analysis of drug nortriptyline and pregabalin using BDS (250mm x 4.6 mm, 5m) C18 column at 210 nm of UV detection. Perchloric acid (0.1%) and acetonitrile in the ratio of 55:45 was used as the mobile phase with a flow rate of 1.0 ml/min and linearity response was established over the concentration range of 5-30 μg/ml for nortriptyline and 37.5-225 μg/ml for pregabalin. The active pharmaceutical ingredients recovered for nortriptyline and pregabalin are in the range of 100.60-101.65% and 100.59-101.74% respectively. The method was validated and was found to be stability indicating and can be successfully utilized for the quantitative analysis of pharmaceutical tablet dosage formulations containing nortriptyline and pregabalin. | en-US |
| dc.format | application/pdf | |
| dc.language | eng | |
| dc.publisher | Sociedad Chilena de Química | en-US |
| dc.relation | http://www.jcchems.com/index.php/JCCHEMS/article/view/192/154 | |
| dc.rights | Copyright (c) 2017 Haritha Potluri, Sreenivasa Rao Battula, Sunandamma Yeturu | en-US |
| dc.rights | https://creativecommons.org/licenses/by-nc-sa/4.0 | en-US |
| dc.source | Journal of the Chilean Chemical Society; Vol 62 No 2 (2017): Journal of the Chilean Chemical Society | en-US |
| dc.source | 0717-9707 | |
| dc.source | 0717-9324 | |
| dc.subject | Nortriptyline | en-US |
| dc.subject | Pregabalin | en-US |
| dc.subject | HPLC | en-US |
| dc.subject | Stability indicating | en-US |
| dc.subject | Validation | en-US |
| dc.title | VALIDATED STABILITY INDICATING RP-HPLC METHOD FOR SIMULTANEOUS DETERMINATION OF NORTRIPTYLINE AND PREGABALIN IN BULK AND COMBINED DOSAGE FORMULATIONS | en-US |
| dc.type | info:eu-repo/semantics/article | |
| dc.type | info:eu-repo/semantics/publishedVersion | |
