CERIUM (IV) AMMONIUM NITRATE (CAN) AS A CATALYST IN WATER: A SIMPLE, PROFICIENT AND GREEN APPROACH FOR THE SYNTHESIS OF TETRAHYDROPYRIMIDINE QUINOLONES

Geramizadegan, Mahsa; Mahdavinia, Gholam Hossein

dc.creator	Geramizadegan, Mahsa
dc.creator	Mahdavinia, Gholam Hossein
dc.date	2017-09-02
dc.date.accessioned	2019-11-13T15:11:36Z
dc.date.available	2019-11-13T15:11:36Z
dc.identifier	http://www.jcchems.com/index.php/JCCHEMS/article/view/313
dc.identifier.uri	https://revistaschilenas.uchile.cl/handle/2250/112616
dc.description	We report here a facile, mild and efficient synthesis of functionalized tetrahydropyrimidine quinolones via one pot three-component condensation of aromatic aldehydes, N,N-dimethyl barbituricacid (barbituricacid), 4-hydroxy-1-methylquinolin-2(1H)-one and using a cerium ammonium nitrate (CAN) as a green catalyst in aqueous media-water (as a green ideal solvent) is described. The significant advantages of this protocol are short reaction time, simple work up procedure and reduced environmental impact, wide substrate scope; generally very good to excellent yields and starting materials are inexpensive and commercially available. The structures of these compounds were established on the basis of IR, 1H NMR, 13C NMR spectra.	en-US
dc.format	application/pdf
dc.language	eng
dc.publisher	Sociedad Chilena de Química	en-US
dc.relation	http://www.jcchems.com/index.php/JCCHEMS/article/view/313/170
dc.rights	Copyright (c) 2017 Journal of the Chilean Chemical Society	en-US
dc.rights	https://creativecommons.org/licenses/by-nc-sa/4.0	en-US
dc.source	Journal of the Chilean Chemical Society; Vol 62 No 3 (2017): Journal of the Chilean Chemical Society	en-US
dc.source	0717-9707
dc.source	0717-9324
dc.subject	Tetrahydropyrimidine quinolones	en-US
dc.subject	One-pot	en-US
dc.subject	Multi-component	en-US
dc.subject	Green chemistry	en-US
dc.subject	Cerium ammonium nitrate	en-US
dc.title	CERIUM (IV) AMMONIUM NITRATE (CAN) AS A CATALYST IN WATER: A SIMPLE, PROFICIENT AND GREEN APPROACH FOR THE SYNTHESIS OF TETRAHYDROPYRIMIDINE QUINOLONES	en-US
dc.type	info:eu-repo/semantics/article
dc.type	info:eu-repo/semantics/publishedVersion

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