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PRELIMINARY PHYTOCHEMICAL STUDY OF THE ECUADORIAN PLANT CROTON ELEGANS KUNTH (EUPHORBIACEAE)

dc.creatorHerrera, Claudia
dc.creatorPérez, Yanely
dc.creatorMorocho, Vladimir
dc.creatorArmijos, Chabaco
dc.creatorMalagón, Omar
dc.creatorBrito, Beatriz
dc.creatorTacán, Marcelo
dc.creatorCartuche, Luis
dc.creatorGilardoni, Gianluca
dc.date2018-04-25
dc.date.accessioned2019-11-13T15:11:46Z
dc.date.available2019-11-13T15:11:46Z
dc.identifierhttp://www.jcchems.com/index.php/JCCHEMS/article/view/590
dc.identifier.urihttps://revistaschilenas.uchile.cl/handle/2250/112668
dc.descriptionThe species Croton elegans Kunth, belonging to the family Euphorbiaceae and known with the common name “mosquera”, is a native medicinal plant of Ecuador. Due to its medical applications, we are interested in secondary metabolite composition. After extraction with hexane and preparation of the alkaloid extract, preparative chromatographic fractionation in both normal and direct phase was performed. 1H NMR, 13C NMR, HSQC and HMBC experiments, together with polarimetric measurements, were conducted in order to characterize the purified compunds. Two triterpene metabolites (friedelin and cycloeucalenol) and two morphinan alkaloids ((+)-pallidine and (+)-O-methylpallidine) were obtained in a pure form. This work represents the first report on the phytochemistry of C. elegans and probably the second publication on the natural (+)-pallidine alkaloid.en-US
dc.formatapplication/pdf
dc.languageeng
dc.publisherSociedad Chilena de Químicaen-US
dc.relationhttp://www.jcchems.com/index.php/JCCHEMS/article/view/590/222
dc.rightsCopyright (c) 2018 Journal of the Chilean Chemical Societyen-US
dc.rightshttps://creativecommons.org/licenses/by-nc-sa/4.0en-US
dc.sourceJournal of the Chilean Chemical Society; Vol 63 No 1 (2018): Journal of the Chilean Chemical Societyen-US
dc.source0717-9707
dc.source0717-9324
dc.subjectCroton elegansen-US
dc.subjectalkaloiden-US
dc.subjectsecondary metaboliteen-US
dc.subjectEcuadoren-US
dc.subjectNMRen-US
dc.subjectmosqueraen-US
dc.subjectfriedelinen-US
dc.subjectcycloeucalenolen-US
dc.subject( )-pallidineen-US
dc.subject( )-O-methylpallidineen-US
dc.subject( )-pallidineen-US
dc.subject( )-O-methylpallidineen-US
dc.titlePRELIMINARY PHYTOCHEMICAL STUDY OF THE ECUADORIAN PLANT CROTON ELEGANS KUNTH (EUPHORBIACEAE)en-US
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion


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