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DETERMINATION OF HYDROXYZINE BY DIFFERENTIAL PULSE ANODIC VOLTAMMETRY USING CARBON PASTE ELECTRODE

dc.creatorZayed, Sayed I. M.
dc.creatorAl-Talhi, Amal A. H.
dc.creatorAl Thagafi, Asmaa E.
dc.date2018-09-12
dc.date.accessioned2019-11-13T15:11:48Z
dc.date.available2019-11-13T15:11:48Z
dc.identifierhttp://www.jcchems.com/index.php/JCCHEMS/article/view/764
dc.identifier.urihttps://revistaschilenas.uchile.cl/handle/2250/112700
dc.descriptionThe electrochemical oxidation of hydroxyzine dihydrochloride at carbon paste electrode has been studied in 0.04 M Britton-Robinson buffer pH 6.2 using cyclic and differential pulse voltammetry. The oxidation process has been shown to irreversible and diffusion controlled with adsorption characterstics. Based on these studies, simple, rapid, and sensitive differential pulse anodic voltammetric method has been developed for the determination of the drug over the concentration range 0.45-5.36 μg/ml, with detection and quantification limits of 0.27 and 0.90 μg/ml hydroxyzine dihydrochloride, respectively. The proposed method was successfully used for quantification of hydroxyzine dihydrochloride in Atarax tablets and spiked human urine.en-US
dc.formatapplication/pdf
dc.languageeng
dc.publisherSociedad Chilena de Químicaen-US
dc.relationhttp://www.jcchems.com/index.php/JCCHEMS/article/view/764/255
dc.rightsCopyright (c) 2018 Journal of the Chilean Chemical Societyen-US
dc.rightshttps://creativecommons.org/licenses/by-nc-sa/4.0en-US
dc.sourceJournal of the Chilean Chemical Society; Vol 63 No 3 (2018): Journal of the Chilean Chemical Societyen-US
dc.source0717-9707
dc.source0717-9324
dc.subjectHydroxyzine dihydrochlorideen-US
dc.subjectdifferential pulse anoding voltammetryen-US
dc.subjectcarbon paste electrodesen-US
dc.subjectpharmaceutical dosage formen-US
dc.subjecthuman urineen-US
dc.titleDETERMINATION OF HYDROXYZINE BY DIFFERENTIAL PULSE ANODIC VOLTAMMETRY USING CARBON PASTE ELECTRODEen-US
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion


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