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dc.creatorSepúlveda C,Cecilia
dc.creatorPuente P,Javier
dc.date2000-12-01
dc.date.accessioned2019-11-14T12:51:41Z
dc.date.available2019-11-14T12:51:41Z
dc.identifierhttps://scielo.conicyt.cl/scielo.php?script=sci_arttext&pid=S0034-98872000001200009
dc.identifier.urihttps://revistaschilenas.uchile.cl/handle/2250/114934
dc.descriptionNatural killer (NK) cells form a unique third group of lymphocytes that differs from T and B cells in surface phenotype, target cell recognition and function. NK cells have two relevant functions, related to the innate immune response against pathogens microorganisms. One is cytotoxicity, mediated by the recognition and lysis of target cells such as virus and bacteria infected-cells. The second NK cell function is to produce cytokines, mainly IFN-g, that can modulate innate and specific immune responses. Cytotoxicity and cytokine secretion contribute to host resistance against microorganisms and both functions are significantly altered in infectious diseases (Rev Méd Chile 2000; 128: 1361-70).
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dc.languagees
dc.publisherSociedad Médica de Santiago
dc.relation10.4067/S0034-98872000001200009
dc.rightsinfo:eu-repo/semantics/openAccess
dc.sourceRevista médica de Chile v.128 n.12 2000
dc.subjectCytokines
dc.subjectKiller cells
dc.subjectLymphocytes
dc.titleCélulas natural killer y el sistema inmune innato en la patología infecciosa


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