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dc.creatorAlvarez L,Manuel
dc.creatorGonzález D,Robinson
dc.creatorBriceño L,Isabel
dc.creatorCofre D,Colomba
dc.creatorLabarca L,Jaime
dc.creatorVial C,Pablo
dc.creatorGarcía C,Patricia
dc.date2001-06-01
dc.date.accessioned2019-11-14T12:52:30Z
dc.date.available2019-11-14T12:52:30Z
dc.identifierhttps://scielo.conicyt.cl/scielo.php?script=sci_arttext&pid=S0034-98872001000600004
dc.identifier.urihttps://revistaschilenas.uchile.cl/handle/2250/115433
dc.descriptionBackground: The clinical parameters for the suspicion of Clostridium difficile infections, namely the use of antimicrobials and diarrhea, have a low predictive value for the diagnosis. Aim: To search other clinical variables and determine a clinical prediction model for (Clostridium difficile diarrhea. Patients and methods: All patients to whom a Clostridium difficile study was requested, were prospectively studied during 5 months. Clinical variables of these patients were registered. The diagnosis of Clostridium difficile was done using the cytotoxicity test in fibroblast cultures. Results: Ninety two patients were analyzed and in 26, the diagnosis of Clostridium difficile was confirmed. A logistic regression model disclosed an age over 60 years old, the presence of mucus in the stools and a temperature over 37.8 °C in the previous 24 h, as significant predictors of the infection. The correlation of the model, between the predicted probability and the observed condition, was 81.5%. Conclusions: The presence of the clinical variables identified in this study are associated with a high probability of an infection by Clostridium difficile in patients with diarrhea and the recent use of antimicrobials (Rev Méd Chile 2001; 129: 620-625)
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dc.languagees
dc.publisherSociedad Médica de Santiago
dc.relation10.4067/S0034-98872001000600004
dc.rightsinfo:eu-repo/semantics/openAccess
dc.sourceRevista médica de Chile v.129 n.6 2001
dc.subjectClostridium difficile
dc.subjectDiarrhea
dc.subjectEnterocolitis, pseudomembranous
dc.titleDiagnóstico de diarrea por Clostridium difficile: en busca de un enfoque clínico más eficiente


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