An annotated checklist of the Sphingidae (hawkmoths) of Bolivia is presented. A total of 189 species and subspecies are confirmed. Locality data derived from specimens in the collections of the Department of Entomology of the Natural History Museum Noel Kempff Mercado of Santa Cruz de la Sierra; the Bolivian Collection of Fauna, La Paz; The Natural History Museum, London; and the Carnegie Museum of Natural History, Pittsburgh, are given. A map of these localities and a synoptic discussion of their geography and ecology are also provided. Data on species not represented in these collections are collated from the publications of J. Haxaire and D. Herbin and presented. Diagnostic features to enable identification of a number of closely related species pairs are described