NEW SYNTHESIS AND CHARACTERIZATION OF THE SODIUM 3- N-ACETYLAMINO-2,4,6-TRIIODOBENZOATE: ANTIBACTERIAL ACTIVITY EVALUATION
Author
KESTERNICH,VICTOR
GARCÍA,PEDRO
MARTÍNEZ,ROLANDO
Abstract
A new synthesis and chemical characterization by mass and infrared spectroscopy of sodium 3-N-acetylamine-2,4,6-triiodobenzoate (sodium acetrizoate), a compound used as contrast agent, has been developed. For its preparation, a new method consisting of three stages has been worked out, using 3-aminobenzoic acid as a substrate. Both the intermediate 4 and the product 5 showed antibacterial activity over Pseudomona aeruginosa ATCC and. Shigella flexneri