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dc.creatorBravo,Hector R.
dc.creatorWeiss-López,Boris
dc.creatorLamborot,Madeleine
dc.creatorCopaja,Sylvia
dc.date2003-12-01
dc.date.accessioned2019-11-14T12:57:40Z
dc.date.available2019-11-14T12:57:40Z
dc.identifierhttps://scielo.conicyt.cl/scielo.php?script=sci_arttext&pid=S0717-97072003000400005
dc.identifier.urihttps://revistaschilenas.uchile.cl/handle/2250/118438
dc.descriptionIn vitro antimicrobial activity of a series of substituted acetanilides against S. aureus, E. coli and C. albicans were measured at two concentrations, 250 mug/ml and 500 mug/ml. Only the structures substituted with halogens in Calpha and electron acceptors in the aromatic ring are bioactive. The results are rationalized in terms of the acid properties of the N-H bond, as calculated using AM1-MO theory
dc.formattext/html
dc.languageen
dc.publisherSociedad Chilena de Química
dc.relation10.4067/S0717-97072003000400005
dc.rightsinfo:eu-repo/semantics/openAccess
dc.sourceJournal of the Chilean Chemical Society v.48 n.4 2003
dc.subjectAcetanilides
dc.subjectantimicrobial activity
dc.subjectAM1-MO calculations
dc.titleCHEMICAL BASIS FOR THE ANTIMICROBIAL ACTIVITY OF ACETANILIDES


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