| dc.creator | Blümel M,Juan Enrique | |
| dc.creator | Branco F,Camil Castelo | |
| dc.creator | Roncagliolo M,María E | |
| dc.creator | Binfa E,Lorena | |
| dc.creator | Sarrá C,Salvador | |
| dc.date | 2003-04-01 | |
| dc.date.accessioned | 2019-11-14T12:59:06Z | |
| dc.date.available | 2019-11-14T12:59:06Z | |
| dc.identifier | https://scielo.conicyt.cl/scielo.php?script=sci_arttext&pid=S0034-98872003000400005 | |
| dc.identifier.uri | https://revistaschilenas.uchile.cl/handle/2250/119292 | |
| dc.description | It is generally accepted that menopause significantly modifies cardiovascular risk. The effects of hormone replacement therapy (HRT) on this risk remain controversial. Aim: To study the prevalence of cardiovascular risk factors (RF) in middle-aged women and their changes with aging, menopause and hormone replacement therapy (HRT). Material and methods: cardiovascular risk factors were assessed in 576 women aged 40 to 59 years in 1991-92. Five years later, 467 of these women were reassessed. Results: Sedentarism (87.2%), dyslipidemias (71.5%), high blood pressure (13.5%), obesity (13.1%), smoking (12.4%) and diabetes (2.8%) were the most prevalent RF. Five years later, the prevalence of hypertension increased to 20.9%, the prevalence of obesity increased to 27.3%, smoking increased to 20.8% and diabetes to 5.9%. The prevalence of dyslipidemia did not change, although triglycerides levels rose from 125.9±56.4 to 136.8±63.5 mg/dl (p <0.001). Sedentarism dropped to 58.8%. Menopause did not deteriorate any of these RF. The use of HRT increased during the 5 years follow-up from 3.8% to 35%. Women on HRT experienced 3% decrease in LDL-cholesterol and 9% increase in HDL-cholesterol levels. Conclusions: Middle aged women included in this cohort have a high prevalence of RF. There is a deterioration with age, but not with menopause. HRT improves the lipid profile (Rev Méd Chile 2003; 131: 381-9). | |
| dc.format | text/html | |
| dc.language | es | |
| dc.publisher | Sociedad Médica de Santiago | |
| dc.relation | 10.4067/S0034-98872003000400005 | |
| dc.rights | info:eu-repo/semantics/openAccess | |
| dc.source | Revista médica de Chile v.131 n.4 2003 | |
| dc.subject | Cardiovascular diseases | |
| dc.subject | Hyperlipidemia | |
| dc.subject | Hormone replacement therapy | |
| dc.subject | Menopause | |
| dc.title | Factores de riesgo cardiovascular en una cohorte de mujeres de edad media | |
