| dc.creator | Oyarzún A,Amaya | |
| dc.creator | Santos M,J Luis | |
| dc.creator | Carrasco P,Elena | |
| dc.creator | Albala B,Cecilia | |
| dc.creator | Salinas T,Alfonso | |
| dc.creator | Pérez B,Francisco | |
| dc.date | 2003-08-01 | |
| dc.date.accessioned | 2019-11-14T12:59:14Z | |
| dc.date.available | 2019-11-14T12:59:14Z | |
| dc.identifier | https://scielo.conicyt.cl/scielo.php?script=sci_arttext&pid=S0034-98872003000800005 | |
| dc.identifier.uri | https://revistaschilenas.uchile.cl/handle/2250/119361 | |
| dc.description | Background : Environmental and genetic factors (viruses, toxins and diet) are involved in the aetiology of type 1 diabetes. Among the dietary factors, the role of breast feeding and exposure to cow's milk proteins deserve special attention. Aim: To determine the anti-BSA-IgG levels in type 1 diabetic children and to analyse the possible association with breast feeding duration, exposure to cow's milk and ß pancreatic auto-antibodies. Patients and methods: Blood samples were collected from 161 diabetic children and 144 controls to measure anti-BSA-IgG level, GAD65, IA-2 and ICA autoantibodies. All children answered a questionnaire about dietary habits during infancy. Results: anti-BSA-IgG was positive (using a cut off point of 25.6 ng/ml) in 98% of diabetic children and 0% of the control population. The length of breast feeding or early exposure to cow's milk did not influence the concentration of anti-BSA-IgG. Positive BSA titers did not increase the ß pancreatic reactivity (ICA+, GAD+, IA-2+). Conclusions: Our data confirm the high frequency of anti-BSA-IgG among diabetic children. However, a specific role in the immunological process of type 1 diabetes cannot be attributed to this protein (Rev Méd Chile 2003; 131: 865-72) | |
| dc.format | text/html | |
| dc.language | es | |
| dc.publisher | Sociedad Médica de Santiago | |
| dc.relation | 10.4067/S0034-98872003000800005 | |
| dc.rights | info:eu-repo/semantics/openAccess | |
| dc.source | Revista médica de Chile v.131 n.8 2003 | |
| dc.subject | Breast feeding | |
| dc.subject | Diabetes Mellitus | |
| dc.subject | insulin-dependent | |
| dc.subject | Insulin antibodies | |
| dc.subject | Milk proteins | |
| dc.title | Anticuerpos anti-albúmina bovina (BSA) en niños diabéticos tipo 1 recién diagnosticados y su asociación con lactancia materna y exposición a leche de vaca | |
