In the current context of scarce financial resources, technology transfer offices are pressured to find ways to increase revenues through technology transfers or reduce expenses with their portfolio of technologies, especially patents. The Patent assessment seeks to detect the market potential of patents for transfer through licensing, abandonment, or maintenance. In this context, the objective of this study is to validate the leading indicators used in the patent evaluation to develop a framework for evaluating academic patent portfolio in the Brazilian context. For this, we used mapping and analysis methods of the current models besides focus group consultations, exploratory factorial analysis, and Analytical Hierarchy Process (AHP) to validate the indicators. The results show that seven factors are determinant in the evaluation of academic patents, having positive implications for the management of Intellectual Property since technology transfer decision-makers can use the factors and their identified weights as value indicators to evaluate patents with the most significant market potential.