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dc.creatorBannura C,Guillermo
dc.creatorCumsille G,Miguel A.
dc.creatorContreras P,Jaime
dc.creatorMelo L,Carlos
dc.creatorBarrera E,Alejandro
dc.creatorReinero C,Macarena
dc.creatorPardo T,Lorena
dc.date2001-03-01
dc.date.accessioned2020-02-17T15:26:26Z
dc.date.available2020-02-17T15:26:26Z
dc.identifierhttps://scielo.conicyt.cl/scielo.php?script=sci_arttext&pid=S0034-98872001000300001
dc.identifier.urihttps://revistaschilenas.uchile.cl/handle/2250/126743
dc.descriptionBackground: Staging of colorectal carcinoma has prognostic value and allows to take decisions about adjuvant therapy and follow up. Prognostic factors are not universally accepted and there are different staging classifications. Aim: To assess the prognostic value of clinical and pathological variables in 224 patients subjected to a curative resection of a colorectal carcinoma. Patients and methods: A retrospective analysis of 99 men and 125 women, aged 23 to 91 years old subjected to a curative resection of a colorectal carcinoma and followed up for a mean of 72 months. Results: Global survival at 60 months was 72%. Univariate analysis showed that tumor localization, vascular permeation, wall infiltration and number of involved lymph nodes had an influence on survival. A Cox regression model disclosed tumor localization (colon versus rectum), a carcinoembrionic antigen over 30 ng/ml, vascular permeation, presence of 1 to 4 involved lymph nodes, or 5 or more lymph nodes and the presence of an apical lymph node as variables with significant prognostic value. Conclusions: Our series confirms the prognostic importance of lymph node involvement. This parameter is incorporated in Jass, GITSG (both modifications of Dukes classification) and TNM staging scores. (Rev Méd Chile 2001; 129: 237-46).
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dc.languagees
dc.publisherSociedad Médica de Santiago
dc.relation10.4067/S0034-98872001000300001
dc.rightsinfo:eu-repo/semantics/openAccess
dc.sourceRevista médica de Chile v.129 n.3 2001
dc.subjectColonic neoplasms
dc.subjectColorectal surgery
dc.subjectRectal neoplasms
dc.titleFactores pronósticos en el cáncer colorrectal: Análisis multivariado de 224 pacientes


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