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dc.creatorGALINDO,MARIO
dc.creatorGONZALEZ,M JULIETA
dc.creatorGALANTI,NORBEL
dc.date2002-01-01
dc.date.accessioned2020-02-17T15:30:56Z
dc.date.available2020-02-17T15:30:56Z
dc.identifierhttps://scielo.conicyt.cl/scielo.php?script=sci_arttext&pid=S0716-97602002000300011
dc.identifier.urihttps://revistaschilenas.uchile.cl/handle/2250/129365
dc.descriptionEchinococcus granulosus is a parasitic platyhelminth that is responsible for cystic hydatid disease. From the inner, germinal layer of hydatid cysts protoscoleces are generated, which are are the infective forms to the dog. Systematic studies on the cell biology of E. granulosus protoscolex formation in natural infections are scarce and incomplete. In the present report we describe seven steps in the development of protoscoleces. Cellular buds formed by a clustering of cells emerge from the germinal layer of hydatid cysts. The buds elongate and the cells at their bases seem to diminish in number. Very early on a furrow appears in the elongated buds, delimiting anterior (scolex) and caudal (body) regions. Hooks are the first fully-differentiated structures formed at the apical region of the nascent scolex. In a more advanced stage, the scolex shows circular projections and depressions that develop into suckers. A cone can later be seen at the center of the hooks, the body is expanded and a structured neck is evident between the scolex and the body. During protoscolex development this parasitic form remains attached to the germinative layer through a stalk. When fully differentiated, the stalk is cut off and the infective protoscolex is now free in the hydatid fluid
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dc.languageen
dc.publisherSociedad de Biología de Chile
dc.relation10.4067/S0716-97602002000300011
dc.rightsinfo:eu-repo/semantics/openAccess
dc.sourceBiological Research v.35 n.3-4 2002
dc.subjectprotoscolex formation
dc.subjecthydatid cyst
dc.titleEchinococcus granulosus protoscolex formation in natural infections


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