Show simple item record

dc.creatorGALLARDO,MILTON
dc.date2003-12-01
dc.date.accessioned2020-02-17T15:31:45Z
dc.date.available2020-02-17T15:31:45Z
dc.identifierhttps://scielo.conicyt.cl/scielo.php?script=sci_arttext&pid=S0716-078X2003000400013
dc.identifier.urihttps://revistaschilenas.uchile.cl/handle/2250/129813
dc.descriptionGenome data analysis indicates that the major evolutionary transitions have been driven by substantial increases in genomic complexity. These increases, accounting for novelty in evolution, have proceeded mainly by gene duplication. This idea, advanced by <A HREF="#OHNO">Ohno (1968)</A>, remains current in the study of several organisms whose genomes have been sequenced. Maize, yeast, and humans contain more paralogons than would be expected to occur by chance, and this supports the contention that gene families were not formed de novo, but by large-scale DNA duplications. Lineage hybridization emerges as an efficient and widespread mechanism to create evolutionary novelty by recruiting redundant genes to new roles. Lateral gene transfer indicates a chimeric composition of prokaryote genomes. This peculiar manner of inheritance blurs the edges of phylogenetic lineages and suggests that the anastomosing and dichotomization of branches play key roles in determining the shape of the tree of life. Adaptive mutations have also enlarged the genetic framework of evolutionary thought by incorporating a new mechanism of gene formation. Moreover, developmental biology has provided solid grounds for understanding organisms as consisting of onto- and epigenetically organized modules. Rapid and drastic changes brought about by the study of developmental genes have discredited the notions that adaptation is achieved exclusively by stepwise allele replacement within populations, and that macroevolutionary change is extrapolated microevolution. Apparently, a broadening, if not a remodeling of the genetic framework in which we understand phylogeny and the evolution of morphological complexity, is emerging through the study of comparative genomics
dc.formattext/html
dc.languageen
dc.publisherSociedad de Biología de Chile
dc.relation10.4067/S0716-078X2003000400013
dc.rightsinfo:eu-repo/semantics/openAccess
dc.sourceRevista chilena de historia natural v.76 n.4 2003
dc.subjectgene duplication
dc.subjectgenome
dc.subjectgenetics
dc.subjectevolution
dc.subjectmacroevolution
dc.subjectevolutionary theory
dc.titleGenome dynamics, genetic complexity and macroevolution


This item appears in the following Collection(s)

Show simple item record