| dc.creator | Cabrera C,María Elena | |
| dc.creator | Marinov M,Neda | |
| dc.creator | Guerra C,Carolina | |
| dc.creator | Morilla,Ricardo | |
| dc.creator | Matutes,Estella | |
| dc.date | 2003-03-01 | |
| dc.date.accessioned | 2020-02-17T15:33:27Z | |
| dc.date.available | 2020-02-17T15:33:27Z | |
| dc.identifier | https://scielo.conicyt.cl/scielo.php?script=sci_arttext&pid=S0034-98872003000300007 | |
| dc.identifier.uri | https://revistaschilenas.uchile.cl/handle/2250/130774 | |
| dc.description | Background: Chronic lymphoproliferative disorders include a variety of diseases which are often a diagnostic problem for clinical hematologists. Aim: To study prospectively the distribution and incidence of chronic lymphoproliferative disorders in Chile and compare them with those of other Western, Latin American and Oriental countries. Patients and methods: A group of 132 patients were studied in a 36 months period (1999-2001), with a panel of monoclonal antibodies. A score for chronic lymphocytic leukemia was employed to differentiate it from other B-cell disorders. Results: The median age was 63 years old (range 32-94). Most patients had B-cell tumors (109) and the rest (23), T-cell tumors (82% vs 18%). Forty five percent of patients with B-cell tumors had a chronic lymphocytic leukemia (CLL), while the others were disseminated lymphomas. The incidence of T-cell tumors was slightly higher than that of other Western countries. Noteworthy is that the most common of these disorders was adult T cell leukemia/lymphoma (ATLL), in concordance with the high HTLV-1 seroprevalence in Chile. Conclusions: A morphologic, immunophenotypic and pathological study in a large number of patients with chronic lymphoproliferative disorders in Chile, shows a relatively low incidence of CLL when compared to other chronic B-cell tumors and a high representation of ATLL associated to HTLV-1 infection, compared with other Western countries. The lower incidence of CLL in our study might be due to patient's selection and/or underdiagnosis of this disease as a substantial proportion of CLL are asymptomatic (Rev Méd Chile 2003; 131: 291-8). | |
| dc.format | text/html | |
| dc.language | es | |
| dc.publisher | Sociedad Médica de Santiago | |
| dc.relation | 10.4067/S0034-98872003000300007 | |
| dc.rights | info:eu-repo/semantics/openAccess | |
| dc.source | Revista médica de Chile v.131 n.3 2003 | |
| dc.subject | Leukemia-Lymphoma | |
| dc.subject | T-cell | |
| dc.subject | acute | |
| dc.subject | HTLV-1-associated | |
| dc.subject | Lymphoma, B-cell | |
| dc.subject | Lymphoproliferative disorders | |
| dc.subject | Lymphoma, T-cell | |
| dc.title | Síndromes linfoproliferativos crónicos en Chile: Estudio prospectivo de 132 casos | |
