| dc.creator | Ordóñez A,María Paz | |
| dc.creator | Nazer H,Julio | |
| dc.creator | Aguila R,Alfredo | |
| dc.creator | Cifuentes O,Lucía | |
| dc.date | 2003-04-01 | |
| dc.date.accessioned | 2020-02-17T15:33:29Z | |
| dc.date.available | 2020-02-17T15:33:29Z | |
| dc.identifier | https://scielo.conicyt.cl/scielo.php?script=sci_arttext&pid=S0034-98872003000400008 | |
| dc.identifier.uri | https://revistaschilenas.uchile.cl/handle/2250/130791 | |
| dc.description | Background: Several maternal diseases, such as diabetes mellitus or high blood pressure, are associated with a higher risk for fetal or neonatal problems. Aim: To study the association between chronic diseases of the mother and congenital malformations. Material and methods: Review of the records of the Latin American Collaborative Study of Congenital Malformations (ECLAMC) at the University of Chile Clinical Hospital. A sample of 383 mothers with a chronic disease was compared with 297 healthy mothers. The presence of congenital malformations in the newborns was studied. The odds ratio (OR) of a mother to have a child with a congenital malformation was calculated. Results: Mothers with bronchial asthma, diabetes mellitus, hypertension and hypothyroidism had an OR over 1 of having a child with a congenital malformation. No association between maternal obesity and offspring malformations was observed. Offspring of diabetic mothers had 8.95 times more probabilities of having a major malformation and 4.95 times more probabilities of having a minor defect. Conclusions: Offspring of mothers with diabetes mellitus, bronchial asthma, hypertension or hypothyroidism have a higher risk of presenting a congenital malformation, when compared with offspring of healthy mothers (Rev Méd Chile 2003; 131: 404-11). | |
| dc.format | text/html | |
| dc.language | es | |
| dc.publisher | Sociedad Médica de Santiago | |
| dc.relation | 10.4067/S0034-98872003000400008 | |
| dc.rights | info:eu-repo/semantics/openAccess | |
| dc.source | Revista médica de Chile v.131 n.4 2003 | |
| dc.subject | Abnormalities | |
| dc.subject | Fetal diseases | |
| dc.subject | Pregnancy | |
| dc.subject | high risk | |
| dc.subject | Pregnancy in diabetes | |
| dc.title | Malformaciones congénitas y patología crónica de la madre.: Estudio ECLAMC 1971-1999 | |
