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Formation of kidney stones of calcium oxalate in mammals

Formación de calculos renales de oxalato cálcico en mamíferos

Author
Neira-Carrillo, Andrónico

Vásquez-Quitral, Patricio

Full text
https://avancesveterinaria.uchile.cl/index.php/ACV/article/view/18285
10.5354/acv.v25i1-2.18285
Abstract
Calcium oxalate (CaOx) is the main inorganic component of urolithiasis and is mainly present in the formation of kidney stones in humans. Additionally, oxalocalcic urolithiasis has become the most frequent type of kidney stones, for instance, oxalocalcic urolithiasis has substantially increased in dogs and cats over the last decades. In urolithiasis, urine is supersaturated with calcium and oxalate ions that promote nucleation, growth and aggregation of CaOx crystals. It is accepted that the presence of acidic macromolecules and inorganic compounds in urine is responsible not only for the molecular processes involved in lithiasis but also for the adhesion and endocytosis by renal epithelial cells. Patients with the tendency to form kidney stones may have an alteration in the structure and/or function of some inhibitors of crystallization. In the current review, we describe some general aspects of epidemiology and pathophysiology of oxalocalcic urolithiasis.    
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Artes, Arquitectura y UrbanismoCiencias Agrarias, Forestales y VeterinariasCiencias Exactas y NaturalesCiencias SocialesDerechoEconomía y AdministraciónFilosofía y HumanidadesIngenieríaMedicinaMultidisciplinarias
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Universidad de ChileUniversidad Católica de ChileUniversidad de Santiago de ChileUniversidad de ConcepciónUniversidad Austral de ChileUniversidad Católica de ValparaísoUniversidad del Bio BioUniversidad de ValparaísoUniversidad Católica del Nortemore

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