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dc.creatorNUNES CHINI,EDUARDO
dc.date2004-01-01
dc.date.accessioned2020-02-17T15:35:43Z
dc.date.available2020-02-17T15:35:43Z
dc.identifierhttps://scielo.conicyt.cl/scielo.php?script=sci_arttext&pid=S0716-97602004000400009
dc.identifier.urihttps://revistaschilenas.uchile.cl/handle/2250/132040
dc.descriptionNicotinic acid adenine dinucleotide phosphate (NAADP) is a potent activator of intracellular Ca2+ release in several vertebrate and invertebrate systems. The role of the NAADP system in physiologicalprocesses is being extensively investigated at the present time. The NAADP receptor and its associated Ca2+ pool have been hypothesized to be important in several physiologicalprocesses including fertilization, T cell activation, and pancreaticsecretion. However, whether NAADP is a new second messenger ora tool for the discovery of a new Ca2+ channel is still an unansweredquestion. Research developed over the last two years has provided some important clues to whether NAADP is or not a physiological cellular messenger. In this short review, I will discuss some of these new findings that are helping us to find an answer to the important question: Is NAADP a second messenger or not?
dc.formattext/html
dc.languageen
dc.publisherSociedad de Biología de Chile
dc.relation10.4067/S0716-97602004000400009
dc.rightsinfo:eu-repo/semantics/openAccess
dc.sourceBiological Research v.37 n.4 2004
dc.subjectNAADP
dc.subjectCa2+
dc.subjectchannels
dc.subjectcADPR
dc.subjectintracellular
dc.subjectsecond messenger
dc.titleTo be or not to be… Nicotinic acid adenine dinucleotide phosphate (NAADP): A new intracellular second messenger?


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