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PYRAZOLE BEARING MOLECULES AS BIOACTIVE SCAFFOLDS: A REVIEW

dc.creatorAziz, Hira
dc.creatorZahoor, Ameer Fawad
dc.creatorAhmad, Sajjad
dc.date2020-03-17
dc.date.accessioned2020-04-08T11:05:14Z
dc.date.available2020-04-08T11:05:14Z
dc.identifierhttp://www.jcchems.com/index.php/JCCHEMS/article/view/1377
dc.identifier.urihttps://revistaschilenas.uchile.cl/handle/2250/133547
dc.descriptionPyrazole being a heterocyclic motif has secured an eccentric status in the field of medicinal chemistry. Pyrazole and its derivatives have tremendous biological applications like anti-cancer, anti-microbial, antiviral, antifungal, anti-inflammatory, analgesic, insecticidal etc. In this review,  some recent developments  have been reported  for the synthesis of biologically active pyrazole  based molecules having biological potential such as anti-SIRT1 and SIRT2, anti-FAAH, anti-NOSs, as liver X receptor partial agonist, CB2 receptor ligand and glucagon receptor antagonists.en-US
dc.formatapplication/pdf
dc.languageeng
dc.publisherSociedad Chilena de Químicaen-US
dc.relationhttp://www.jcchems.com/index.php/JCCHEMS/article/view/1377/376
dc.rightsCopyright (c) 2020 Journal of the Chilean Chemical Societyen-US
dc.rightshttps://creativecommons.org/licenses/by-nc-sa/4.0en-US
dc.sourceJournal of the Chilean Chemical Society; Vol 65 No 1 (2020): Journal of the Chilean Chemical Society; 4746-4753en-US
dc.source0717-9707
dc.source0717-9324
dc.subjectPyrazoleen-US
dc.subjectAnti-enzymaticen-US
dc.subjectinsecticidal activityen-US
dc.subjectanalgesic activityen-US
dc.subjectAnti-inflammatory activityen-US
dc.subjectAntimicrobial activityen-US
dc.subjectAnticancer activityen-US
dc.titlePYRAZOLE BEARING MOLECULES AS BIOACTIVE SCAFFOLDS: A REVIEWen-US
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion


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