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Electrochemotherapy in the treatment of neoplasms in dogs and cats

dc.creatorRangel, Marcelo M.M.
dc.creatorLuz, Jean C.S.
dc.creatorOliveira, Krishna D.
dc.creatorOjeda, Javier
dc.creatorFreytag, Jennifer O.
dc.creatorSuzuki, Daniela O.
dc.date2019-05-09
dc.date.accessioned2020-07-14T19:03:34Z
dc.date.available2020-07-14T19:03:34Z
dc.identifierhttp://revistas.uach.cl/index.php/australjvs/article/view/5039
dc.identifier10.4067/S0719-81322019000200045
dc.identifier.urihttps://revistaschilenas.uchile.cl/handle/2250/143625
dc.descriptionElectrochemotherapy (ECT) is a technique that combines chemotherapy with local application of specific electric pulses with the aim of increasing the permeability of the plasma membrane in a reversible way, improving the influx of chemotherapeutic drugs into the cytoplasm and potentiating their cytotoxic effects. This technique has broadened the range of possible treatments for oncological patients, either on its own or as adjuvant to surgical procedures. It is especially useful in tumors located in regions with only a small surgical safety margin, such as the limb extremities, skull, oral cavity, neck and perianal region, among others. ECT makes it feasible to perform procedures more conservatively, or even to perform otherwise infeasible procedures, by expanding the margins without removing healthy tissues. The objective of this paper is to provide a brief bibliographic review of the principles, applications and future possibilities of electrochemotherapy, helping to disseminate pertinent information about this relatively new technique for the treatment of cancer.en-US
dc.descriptionElectrochemotherapy (ECT) is a technique that combines chemotherapy with local application of specific electric pulses with the aim of increasing the permeability of the plasma membrane in a reversible way, improving the influx of chemotherapeutic drugs into the cytoplasm and potentiating their cytotoxic effects. This technique has broadened the range of possible treatments for oncological patients, either on its own or as adjuvant to surgical procedures. It is especially useful in tumors located in regions with only a small surgical safety margin, such as the limb extremities, skull, oral cavity, neck and perianal region, among others. ECT makes it feasible to perform procedures more conservatively, or even to perform otherwise infeasible procedures, by expanding the margins without removing healthy tissues. The objective of this paper is to provide a brief bibliographic review of the principles, applications and future possibilities of electrochemotherapy, helping to disseminate pertinent information about this relatively new technique for the treatment of cancer.es-ES
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dc.languageeng
dc.publisherFacultad de Ciencias Veterinarias - Universidad Austral de Chilees-ES
dc.relationhttp://revistas.uach.cl/index.php/australjvs/article/view/5039/5735
dc.rightsDerechos de autor 2019 Austral Journal of Veterinary Scienceses-ES
dc.sourceAustral Journal of Veterinary Sciences; Vol. 51 Núm. 2 (2019); 45-51en-US
dc.sourceAustral Journal of Veterinary Sciences; Vol. 51 Núm. 2 (2019); 45-51es-ES
dc.source0719-8132
dc.source0719-8000
dc.titleElectrochemotherapy in the treatment of neoplasms in dogs and catsen-US
dc.titleElectrochemotherapy in the treatment of neoplasms in dogs and catses-ES
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion


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