| dc.creator | Oyarzo, Natacha | |
| dc.creator | Riveros, MarÃa | |
| dc.creator | Andaur, Constanza | |
| dc.creator | Liberona, Jessica | |
| dc.creator | Cortés, VÃctor | |
| dc.date | 2019-01-28 | |
| dc.date.accessioned | 2021-08-17T17:09:24Z | |
| dc.date.available | 2021-08-17T17:09:24Z | |
| dc.identifier | https://arsmedica.cl/index.php/MED/article/view/1524 | |
| dc.identifier | 10.11565/arsmed.v44i1.1524 | |
| dc.identifier.uri | https://revistaschilenas.uchile.cl/handle/2250/173573 | |
| dc.description | Background: diabetes and periodontitis are common comorbidities; however, the clinical implications of this association remain only partially known. This study was aimed to characterize the periodontal status of type 2 diabetic (T2D) patients and its correlation with metabolic and inflammatory parameters. Methods: patients (n = 30) with 5 or less years since the diagnosis of T2D (18 – 65 years old) were recruited. Anthropometric (Body Mass Index, BMI), metabolic (fasting glucose, glycated hemoglobin, insulin, HOMA-IR, HDL, LDL and total cholesterol, triglycerides) and inflammatory parameters (ultrasensitive C reactive protein, usCRP) were quantified. Periodontal evaluation included clinical attachment level (CAL), probing depth (PD), gingival level (GL) and bleeding on probing (BOP) average. Statistical significance was assessed by Mann-Whitney and Spearman correlation tests. Results: mean values of BOP, CAL, PD and GL were 39.3, 2.8, 2.8, and 0.1, respectively. BOP significantly correlated with BMI and HOMA-IR and was higher in patients with elevated usCRP >3 mg/L (p<0.05). Age and duration of T2D directly and inversely correlated with CAL and GL, respectively. BOP correlated with HOMA-IR and usCRP but not with patients´age, duration of T2D or BMI. Conclusions: in patients with recent diagnosis of T2D, BOP is associated with usCRP and HOMA-IR levels, suggesting that periodontal inflammation promotes insulin resistance possibly by increasing systemic inflammation. | es-ES |
| dc.format | application/pdf | |
| dc.language | spa | |
| dc.publisher | Facultad de Medicina, Pontificia Universidad Católica de Chile | es-ES |
| dc.relation | https://arsmedica.cl/index.php/MED/article/view/1524/1352 | |
| dc.rights | Derechos de autor 2019 ARS MEDICA Revista de Ciencias Médicas | es-ES |
| dc.source | ARS MEDICA REVISTA DE CIENCIAS MEDICAS; Vol. 44 No. 1 (2019); 6-12 | en-US |
| dc.source | ARS MEDICA Revista de Ciencias Médicas; Vol. 44 Núm. 1 (2019); 6-12 | es-ES |
| dc.source | 0719-1855 | |
| dc.source | 0718-1051 | |
| dc.source | 10.11565/arsmed.v44i1 | |
| dc.subject | diabetes | es-ES |
| dc.subject | periodontitis | es-ES |
| dc.subject | C reactive protein | es-ES |
| dc.subject | insulin resistance | es-ES |
| dc.subject | inflammation | es-ES |
| dc.subject | chronic disease | es-ES |
| dc.title | Periodontal inflammation correlates with systemic inflammation and insulin resistance in patients with recent diagnosis of type 2 diabetes | es-ES |
| dc.type | info:eu-repo/semantics/article | |
| dc.type | info:eu-repo/semantics/publishedVersion | |
| dc.type | artÃculo revisado por pares | es-ES |
