Sjögren's syndrome (SS) is an autoimmune disease characterized by a chronic inflammatory process of the exocrine glands, whose phenotypic expression is keratoconjunctivitis sicca and xerostomia, which entails the development of caries, periodontal disease and bacterial and fungal infections. These patients are at high risk cariogenic, being of great interest and concern in dental practice, where treatment is mainly symptomatic. The present case is a patient of 65 years of age diagnosed with SS 8 years; which has multiple cavities and root fragments in mandibular teeth and jaws, which radiographic examinations and doctors indicated, multiple extractions are performed in lower sector and in the same operation five implants are installed, three months are expected to allow osseointegration to further rehabilitate a prosthesis implants ad modum type on stilts and in the upper section will be rehabilitated with wax composites prior diagnosis and test mock up to reach the occlusal plane and recover functionality and aesthetics